HAMAP

Accession	MF_01094
Dates	27-NOV-2003 (Created) 2-DEC-2011 (Last updated, Version 19)

Data class

Protein

Predictors

HAMAP; MF_01094; [distribution of match scores in UniProtKB];[seed alignment for MF_01094]

Names

MtrB

Identifier

MTRB

Protein name

RecName: Full=Tetrahydromethanopterin S-methyltransferase subunit B; EC=2.1.1.86; AltName: Full=N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B;

Gene name

mtrB

FUNCTION: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step (By similarity).

CATALYTIC ACTIVITY: 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate.

PATHWAY: One-carbon metabolism; methanogenesis from CO(2); methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 2/2.

SUBUNIT: The complex is composed of 8 subunits; mtrA, mtrB, mtrC, mtrD, mtrE, mtrF, mtrG and mtrH (By similarity).

SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein (Potential).

SIMILARITY: Belongs to the mtrB family.

Pfam	PF05440; MtrB; 1;
General	Transmembrane; -; 1; trigger=Yes;

Methanogenesis.

One-carbon metabolism, Transferase, Methyltransferase, Cell membrane, Membrane, Transmembrane, Transmembrane helix.

GO:0030269; Molecular function: tetrahydromethanopterin S-methyltransferase activity.
GO:0006730; Biological process: one-carbon metabolic process.

GO:0015948; Biological process: methanogenesis.

GO:0005886; Cellular component: plasma membrane.

Size range:	100-112 amino acids
Related UniRules:	None
Template:	Q59584 (MTRB_METTM)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None