HAMAP rule MF_01116

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01116
Accession	MF_01116
Dates	27-NOV-2003 (Created) 3-SEP-2024 (Last updated, Version 28)
Name	TSR3
Scope(s)	Archaea
Template(s)	Q12094 (TSR3_YEAST); E1QU22 (TSR3_VULDI); [ Recover all ]
Triggered by	case c? <OC:Archaea> HAMAP; MF_01116 (Get profile general information and statistics) end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	TSR3
Protein name	RecName: Full=16S rRNA aminocarboxypropyltransferase; EC=2.5.1.157;

Comments [?]

FUNCTION	Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3- carboxypropyl) pseudouridine (m1acp3-Psi).
CATALYTIC ACTIVITY	Reaction=an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine in rRNA + S-methyl-5'-thioadenosine + H(+); Xref=Rhea:RHEA:63296, Rhea:RHEA- COMP:11634, Rhea:RHEA-COMP:16310, ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:59789, ChEBI:CHEBI:74890, ChEBI:CHEBI:146234; EC=2.5.1.157;
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the TDD superfamily. TSR3 family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm

GO:1904047; Molecular function:S-adenosyl-L-methionine binding

GO:0000455; Biological process:enzyme-directed rRNA pseudouridine synthesis

GO:0006364; Biological process:rRNA processing

Cross-references [?]

Pfam	PF04034; Ribo_biogen_C; 1;
Pfam	PF04068; RLI; 1;

Features [?]

From: TSR3_VULDI (E1QU22)

Key

From

Description

Tag

Condition

FTGroup

BINDING