Annotation rule MF_01132
Send feedback

General rule information [?]

Accession MF_01132
Dates 2-FEB-2004 (Created)
17-DEC-2013 (Last updated, Version 19)
Name SpxA
Scope Bacteria; Firmicutes

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
SPX
Protein name
RecName: Full=Regulatory protein Spx;
Gene name
spxA

Comments [?]

Function Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity).
Subcellular location Cytoplasm (By similarity).
Similarity Belongs to the ArsC family. Spx subfamily.

Keywords [?]

case <FT:1>
end case

Gene Ontology [?]

GO:0045892; Biological process: negative regulation of transcription, DNA-templated.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF03960; ArsC; 1;
TIGRFAMs TIGR01617; ArsC_related; 1;

Features [?]

From: SPX_BACSU (O31602)
Key     From     To       Description   Tag   Condition   FTGroup
DISULFID     10     13       Redox-active (Potential)     C-x-x-C  

Additional information [?]

Size range 128-137 amino acids
Related rules None
Template O31602 (SPX_BACSU)
Fusion None