HAMAP

Accession	MF_01165
Dates	16-JUN-2005 (Created) 9-SEP-2011 (Last updated, Version 26)

Data class

Protein

Predictors

HAMAP; MF_01165; [distribution of match scores in UniProtKB];[seed alignment for MF_01165]

Names

ArnT_transfer

Identifier

ARNT

Protein name

RecName: Full=Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase; EC=2.4.2.43; AltName: Full=4-amino-4-deoxy-L-arabinose lipid A transferase; AltName: Full=Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; AltName: Full=Undecaprenyl phosphate-alpha-L-Ara4N transferase;

Gene name

arnT

FUNCTION: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity).

CATALYTIC ACTIVITY: 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.

PATHWAY: Lipopolysaccharide metabolism; 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis.

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).

SIMILARITY: Belongs to the glycosyltransferase 83 family.

Pfam	PF02366; PMT; 1;
General	Transmembrane; -; 10-13; trigger=Yes;

Cell inner membrane.

Cell membrane, Glycosyltransferase, Lipid A biosynthesis, Lipid synthesis, Lipopolysaccharide biosynthesis, Membrane, Transferase, Transmembrane, Transmembrane helix.

GO:0016740; Molecular function: transferase activity.
GO:0009245; Biological process: lipid A biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

Size range:	533-583 amino acids
Related UniRules:	None
Template:	P76473 (ARNT_ECOLI); O52327 (ARNT_SALTY): [Recover all]
Scope:	Bacteria; Gammaproteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in PROMH, PSEF5, PSEPF, SODGM
Plasmid encoded:	None