HAMAP

Accession	MF_01173
Dates	9-NOV-2006 (Created) 31-OCT-2011 (Last updated, Version 11)

Data class

Protein

Predictors

HAMAP; MF_01173; [distribution of match scores in UniProtKB];[seed alignment for MF_01173]

Names

AstC_aminotrans_3

Identifier

ASTC

Protein name

RecName: Full=Succinylornithine transaminase; EC=2.6.1.81; AltName: Full=Succinylornithine aminotransferase;

Gene name

astC, argM

FUNCTION: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase (By similarity).

CATALYTIC ACTIVITY: N(2)-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate.

COFACTOR: Pyridoxal phosphate (By similarity).

PATHWAY: Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 3/5.

SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.

PROSITE	PS00600; AA_TRANSFER_CLASS_3; 1;
Pfam	PF00202; Aminotran_3; 1;
TIGRFAMs	TIGR00707; ArgD; 1;

Aminotransferase, Arginine metabolism, Pyridoxal phosphate, Transferase.

GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0008483; Molecular function: transaminase activity.
GO:0019544; Biological process: arginine catabolic process to glutamate.

From: ASTC_ECOLI (P77581)
Key		From		To		Description		Condition		FTGroup
MOD_RES		252		252		N6-(pyridoxal phosphate)lysine (By similarity)		K

Size range:	402-414 amino acids
Related UniRules:	MF_01107 (ARGD)
Template:	P77581 (ASTC_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None