HAMAP

Accession	MF_01176
Dates	23-NOV-2006 (Created) 31-OCT-2011 (Last updated, Version 9)

Data class

Protein

Predictors

HAMAP; MF_01176; [distribution of match scores in UniProtKB];[seed alignment for MF_01176]

Names

HTH-type_IscR

Identifier

ISCR

Protein name

RecName: Full=HTH-type transcriptional regulator iscR;

Gene name

iscR

FUNCTION: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins (By similarity).

COFACTOR: Binds 1 2Fe-2S cluster (By similarity).

SIMILARITY: Contains 1 HTH rrf2-type DNA-binding domain.

PROSITE	PS01332; HTH_RRF2_1; 1; PS51197; HTH_RRF2_2; 1; trigger=PRU00540;
Pfam	PF02082; Rrf2; 1;
TIGRFAMs	TIGR02010; IscR; 1; TIGR00738; Rrf2_super; 1;

2Fe-2S.

Activator, DNA-binding.

Iron, Iron-sulfur, Metal-binding.

Repressor, Transcription, Transcription regulation.

GO:0003690; Molecular function: double-stranded DNA binding.

GO:0005506; Molecular function: iron ion binding.

GO:0003700; Molecular function: sequence-specific DNA binding transcription factor activity.
GO:0006355; Biological process: regulation of transcription, DNA-dependent.

From: ISCR_ECOLI (P0AGK8)
Key		From		To		Description		Condition		FTGroup
METAL		92		92		Iron-sulfur (2Fe-2S) (Potential)		C		1
METAL		98		98		Iron-sulfur (2Fe-2S) (Potential)		C		1
METAL		104		104		Iron-sulfur (2Fe-2S) (Potential)		C		1

Size range:	162-173 amino acids
Related UniRules:	None
Template:	P0AGK8 (ISCR_ECOLI)
Scope:	Bacteria; Gammaproteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None