Annotation rule MF_01180
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General rule information [?]

Accession MF_01180
Dates 15-OCT-2008 (Created)
26-SEP-2014 (Last updated, Version 10)
Name FliT
Scope Bacteria; Enterobacteriaceae
Template P0A1N2 (FLIT_SALTY)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
FLIT
Protein name
RecName: Full=Flagellar protein FliT;
Gene name
fliT

Comments [?]

Function Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
Subunit Homodimer. Interacts with FliD and FlhC.
Subcellular location Cytoplasm, cytosol.
Similarity Belongs to the FliT family.

Keywords [?]


Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:1902209; Biological process: negative regulation of bacterial-type flagellum assembly.
GO:0006457; Biological process: protein folding.

Cross-references [?]

Pfam PF05400; FliT; 1;

Features [?]

From: FLIT_SALTY (P0A1N2)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     1     50       Required for homodimerization        
REGION     60     98       FliD binding        

Additional information [?]

Size range 120-126 amino acids
Related rules None
Fusion None