HAMAP

Accession	MF_01190
Dates	15-JUN-2007 (Created) 2-DEC-2011 (Last updated, Version 8)

Data class

Protein

Predictors

HAMAP; MF_01190; [distribution of match scores in UniProtKB];[seed alignment for MF_01190]

Names

HTH-type_FabR

Identifier

FABR

Protein name

RecName: Full=HTH-type transcriptional repressor fabR;

Gene name

fabR

FUNCTION: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer (By similarity).

SUBUNIT: Homodimer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Contains 1 HTH tetR-type DNA-binding domain.

PROSITE	PS01081; HTH_TETR_1; 1; PS50977; HTH_TETR_2; 1; trigger=PRU00335;
Pfam	PF00440; TetR_N; 1;

Cytoplasm, DNA-binding, Fatty acid biosynthesis, Lipid synthesis, Repressor, Transcription, Transcription regulation.

GO:0003700; Molecular function: sequence-specific DNA binding transcription factor activity.
GO:0006633; Biological process: fatty acid biosynthetic process.
GO:0045717; Biological process: negative regulation of fatty acid biosynthetic process.
GO:0006355; Biological process: regulation of transcription, DNA-dependent.
GO:0005737; Cellular component: cytoplasm.

Size range:	210-215 amino acids
Related UniRules:	None
Template:	P0ACU5 (FABR_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None