HAMAP rule MF_01190
General rule information
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Accession | MF_01190 |
Dates | 15-JUN-2007 (Created)
28-JUN-2022 (Last updated, Version 21) |
Name | HTH_type_FabR |
Scope(s) |
Bacteria Enterobacterales |
Template(s) | P0ACU5 (FABR_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_01190 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | FABR |
Protein name | RecName: Full=HTH-type transcriptional repressor FabR; |
Gene name | Name=fabR; |
Comments
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FUNCTION | Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. |
SUBUNIT | Homodimer. |
SUBCELLULAR LOCATION | Cytoplasm. |
Keywords
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Cytoplasm |
DNA-binding |
Fatty acid biosynthesis |
Fatty acid metabolism |
Lipid biosynthesis |
Lipid metabolism |
Repressor |
Transcription |
Transcription regulation |
Gene Ontology
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GO:0003700; Molecular function:DNA-binding transcription factor activity |
GO:0006633; Biological process:fatty acid biosynthetic process |
GO:0045717; Biological process:negative regulation of fatty acid biosynthetic process |
GO:0006355; Biological process:regulation of DNA-templated transcription |
GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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Additional information
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Size range | 200-250 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |