HAMAP

Accession	MF_01215
Dates	10-JUN-2002 (Created) 5-JAN-2012 (Last updated, Version 20)

Name	OMPdecase_type2

Scope

Bacteria Archaea

Triggered by

HAMAP; MF_01215 (Get profile general information and statistics)

Identifier

PYRF

Protein name

RecName: Full=Orotidine 5'-phosphate decarboxylase; EC=4.1.1.23; AltName: Full=OMP decarboxylase; Short=OMPDCase; Short=OMPdecase;

Gene name

pyrF

CATALYTIC ACTIVITY	Orotidine 5'-phosphate = UMP + CO(2).
PATHWAY	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate; step 2/2.
SIMILARITY	Belongs to the OMP decarboxylase family. Type 2 subfamily.

Lyase
Decarboxylase
Pyrimidine biosynthesis

GO:0004590; Molecular function: orotidine-5'-phosphate decarboxylase activity.
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process.

Pfam	PF00215; OMPdecase; 1;
PROSITE	PS00156; OMPDECASE; 1;

From: PYRF_DEIRA (Q9RSC5)

Key

From

To

Description

Tag

Condition

FTGroup

ACT_SITE

92

92

Proton donor (By similarity)

K

Size range:	267-307 amino acids
Related Rules:	MF_01200 (PYRF)
Templates:	P0A5M7 (PYRF_MYCBO); P96076 (PYRF_THET2): [Recover all]
Fusion:	Nter: None; Cter: MF_01208 (pyrE)
Comments:	Divergent NOSS1; sequence not included in alignment

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