HAMAP

Accession	MF_01215
Dates	10-JUN-2002 (Created) 22-OCT-2010 (Last updated, Version 19)

Data class

Protein

Predictors

HAMAP; MF_01215; [distribution of match scores in UniProtKB];[seed alignment for MF_01215]

Names

OMPdecase_type2

Identifier

PYRF

Protein name

RecName: Full=Orotidine 5'-phosphate decarboxylase; EC=4.1.1.23; AltName: Full=OMP decarboxylase; Short=OMPDCase; Short=OMPdecase;

Gene name

pyrF

CATALYTIC ACTIVITY: Orotidine 5'-phosphate = UMP + CO(2).

PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

SIMILARITY: Belongs to the OMP decarboxylase family. Type 2 subfamily.

Pfam	PF00215; OMPdecase; 1;
PROSITE	PS00156; OMPDECASE; 1;

Lyase, Decarboxylase, Pyrimidine biosynthesis.

GO:0004590; Molecular function: orotidine-5'-phosphate decarboxylase activity.
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process.

From: PYRF_DEIRA (Q9RSC5)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		92		92		Proton donor (By similarity)		K

Size range:	267-307 amino acids
Related UniRules:	MF_01200 (PYRF)
Template:	P0A5M7 (PYRF_MYCBO); P96076 (PYRF_THET2): [Recover all]
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: MF_01208 (pyrE)
Duplicate:	None
Plasmid encoded:	None
Comments:	Divergent NOSS1; sequence not included in alignment