HAMAP

Accession	MF_01216
Dates	24-JUN-2002 (Created) 22-DEC-2010 (Last updated, Version 25)

Data class

Protein

Predictors

HAMAP; MF_01216; [distribution of match scores in UniProtKB];[seed alignment for MF_01216]

Names

Azoreductase_type1

Identifier

AZOR

Protein name

RecName: Full=FMN-dependent NADH-azoreductase; EC=1.7.-.-; AltName: Full=Azo-dye reductase; AltName: Full=FMN-dependent NADH-azo compound oxidoreductase;

Gene name

azoR

FUNCTION: Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).

COFACTOR: Binds 1 FMN per subunit (By similarity).

SUBUNIT: Homodimer (By similarity).

SIMILARITY: Belongs to the azoreductase type 1 family.

Pfam	PF02525; Flavodoxin_2; 1;
PRINTS	PR00453; VWFADOMAIN; 1;

Flavoprotein, FMN, NAD, Oxidoreductase.

GO:0008752; Molecular function: FMN reductase activity.
GO:0009055; Molecular function: electron carrier activity.
GO:0010181; Molecular function: FMN binding.
GO:0016652; Molecular function: oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor.

From: AZOR_ECOLI (P41407)
Key		From		To		Description		Condition		FTGroup
NP_BIND		16		18		FMN (By similarity)		S-Q-S
NP_BIND		96		99		FMN (By similarity)		M-Y-N-F
NP_BIND		140		145		FMN (By similarity)		S-R-G-G-I-H
BINDING		10		10		FMN (By similarity)		S

Size range:	192-220 amino acids
Related UniRules:	None
Template:	P41407 (AZOR_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in ANAVT, BACAN, BACC1, BACCR, BACCZ, BACHD, BACHK, BACLD, BACSU, BURS3, CLOAB, CLOPE, COLP3, HAHCH, IDILO, JANSC, LACLA, LISIN, LISMF, LISMO, MESFL, PHOPR, PSEAE, PSEF5, PSEPF, PSEPK, PSEPM, CUPPJ, RHIEC, XANAC, XANC5
Plasmid encoded:	in ANAVT, RALSO, RHIEC
Comments:	Divergent STRCO and first copy in CLOAB and CLOPE; sequences not included in alignment and not taken into account in size range. In some species there are many duplicates.