HAMAP rule MF_01217
General rule information
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| Accession | MF_01217 |
| Dates | 26-JUN-2002 (Created)
8-JAN-2024 (Last updated, Version 40) |
| Name | Acyl_carrier |
| Scope(s) |
Bacteria Plastid |
| Template(s) | P0A6A8 (ACP_ECOLI); P80643 (ACP_BACSU); P20803 (ACP_ANAVA); P94123 (ACP_AZOBR); O54439 (ACP1_PSEAE); Q9RG22 (ACP_RHILE); P19372 (ACP_RHIME); P12784 (ACP_CERSP); P11830 (ACP_SACEN); P20804 (ACP_SYNY3); [ Recover all ] |
| Triggered by |
HAMAP; MF_01217 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ACP |
| Protein name | RecName: Full=Acyl carrier protein; Short=ACP; |
| Gene name | Name=acpP; |
Comments
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| FUNCTION | Carrier of the growing fatty acid chain in fatty acid biosynthesis. |
| PATHWAY | Lipid metabolism; fatty acid biosynthesis. |
| case <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| case not <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| end case | |
| PTM | 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group. |
| SIMILARITY | Belongs to the acyl carrier protein (ACP) family. |
Keywords
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| case not <OG:Chloroplast> | |
| Cytoplasm | |
| end case | |
| Fatty acid biosynthesis | |
| Fatty acid metabolism | |
| Lipid biosynthesis | |
| Lipid metabolism | |
| Phosphopantetheine | |
| Phosphoprotein | |
Gene Ontology
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| GO:0000036; Molecular function:acyl carrier activity | |
| GO:0006633; Biological process:fatty acid biosynthetic process | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
| case not <OG:Chloroplast> | |
| GO:0005737; Cellular component:cytoplasm | |
| end case | |
Cross-references
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| Pfam | PF00550; PP-binding; 1; |
| NCBIfam | TIGR00517; Acyl_carrier; 1; |
| PROSITE | PS00012; PHOSPHOPANTETHEINE; 1; |
| PROSITE | PS50075; CARRIER; 1; |
Features
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| From: ACP_ECOLI (P0A6A8) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 37 | 37 | /note="O-(pantetheine 4'-phosphoryl)serine" | S | ||||||||
Additional information
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| Size range | 69-95 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Longer C-terminal in MYCTU, MYCLE and in the second copy in CLOAB; sequences not shown in alignment and not taken into account in size range. Longer sequence in CYAPA; not shown in alignment, and not taken into account in size range. |