HAMAP rule MF_01224
General rule information
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Accession | MF_01224 |
Dates | 4-SEP-2002 (Created)
1-JUN-2023 (Last updated, Version 28) |
Name | MoaC |
Scope(s) |
Bacteria Archaea |
Template(s) | P0A738 (MOAC_ECOLI); Q2FVX9 (MOAC_STAA8); [ Recover all ] |
Triggered by |
case c? <OC:Bacteria>
HAMAP; MF_01224_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_01224_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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Identifier | MOAC |
case <OC:Bacteria> | |
Protein name | RecName: Full=Cyclic pyranopterin monophosphate synthase; EC=4.6.1.17; AltName: Full=Molybdenum cofactor biosynthesis protein C; |
end case | |
case <OC:Archaea> | |
Protein name | RecName: Full=Probable cyclic pyranopterin monophosphate synthase; EC=4.6.1.17; AltName: Full=Molybdenum cofactor biosynthesis protein C; |
end case | |
Gene name | Name=moaC; |
Comments
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FUNCTION | Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP). |
CATALYTIC ACTIVITY | Reaction=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate; Xref=Rhea:RHEA:49580, ChEBI:CHEBI:33019, ChEBI:CHEBI:59648, ChEBI:CHEBI:131766; EC=4.6.1.17; |
PATHWAY | Cofactor biosynthesis; molybdopterin biosynthesis. |
SUBUNIT | Homohexamer; trimer of dimers. |
SIMILARITY | Belongs to the MoaC family. |
Keywords
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Gene Ontology
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GO:0061799; Molecular function:cyclic pyranopterin monophosphate synthase activity |
GO:0006777; Biological process:Mo-molybdopterin cofactor biosynthetic process |
Cross-references
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Features
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From: MOAC_ECOLI (P0A738) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
case <OC:Bacteria> | ||||||||||||
BINDING | 75 | 77 | /ligand="substrate" | [LMYF]-x-H | ||||||||
BINDING | 113 | 114 | /ligand="substrate" | [MI]-E | ||||||||
ACT_SITE | 128 | 128 | D | |||||||||
end case | ||||||||||||
From: MOAC_METTH (O26900) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
case <OC:Archaea> | ||||||||||||
BINDING | 77 | 79 | /ligand="substrate" | [LMY]-x-H | ||||||||
BINDING | 113 | 114 | /ligand="substrate" | M-[ED] | ||||||||
ACT_SITE | 128 | 128 | D | |||||||||
end case |
Additional information
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Size range | 143-163 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: MF_01226 (moaB); MF_00316 (mobA); <Unknown> |
Comments | Divergent PYRAE; sequence not included in alignment and not taken into account in size range. Unknown C-terminal domain in AQUAE. |