Annotation rule MF_01244
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General rule information [?]

Accession MF_01244
Dates 5-JUN-2003 (Created)
16-APR-2013 (Last updated, Version 17)
Name Arch_DHQ_synthase
Scope Bacteria; Aquificae
Archaea
Templates Q58646 (DHQS_METJA); Q6M1B0 (DHQS_METMP): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

case <OC:Archaea>
Identifier
DHQS
Protein name
RecName: Full=3-dehydroquinate synthase;
Short=DHQ synthase;
EC=1.4.1.24;
AltName: Full=3-dehydroquinate synthase II;
Gene name
aroB'
end case
case <OC:Bacteria>
Identifier
DHQSH
Protein name
RecName: Full=3-dehydroquinate synthase homolog;
EC=1.4.1.-;
end case

Comments [?]

case <OC:Archaea>
Function Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis (By similarity).
Catalytic activity 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H(2)O + NAD(+) = 3-dehydroquinate + NH(3) + NADH.
end case
Similarity Belongs to the archaeal-type DHQ synthase family.

Keywords [?]


Gene Ontology [?]

GO:0016639; Molecular function: oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor.
GO:0051287; Molecular function: NAD binding.
GO:0009073; Biological process: aromatic amino acid family biosynthetic process.

Cross-references [?]

Pfam PF01959; DHQS; 1;

Additional information [?]

Size range 323-402 amino acids
Related rules None
Fusion None