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HAMAP annotation rule: MF_01254
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General rule information

Accession MF_01254
Dates 16-DEC-2004 (Created)
22-OCT-2010 (Last updated, Version 15)
Data class Protein
Predictors HAMAP; MF_01254; [distribution of match scores in UniProtKB];[seed alignment for MF_01254]
Names Fucose_iso


Propagated annotation

Identifier, protein and gene names
Identifier FUCI
Protein name
RecName: Full=L-fucose isomerase;
EC=5.3.1.25;
AltName: Full=6-deoxy-L-galactose isomerase;
AltName: Full=FucIase;
Gene name fucI
Comments
FUNCTION: Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity).
CATALYTIC ACTIVITY: L-fucose = L-fuculose.
COFACTOR: Manganese (By similarity).
PATHWAY: Carbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 1/3.

case <OC:Enterobacteriaceae>
SUBUNIT: Homohexamer (By similarity).
end case

SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the L-fucose isomerase family.
Cross-references
Pfam PF02952; Fucose_iso_C; 1;
TIGRFAMs TIGR01089; fucI; 1;
Keywords
Cytoplasm, Carbohydrate metabolism, Fucose metabolism, Isomerase.

case <FT:3> and <FT:4> and <FT:5>
Manganese, Metal-binding.
end case

Gene Ontology
GO:0008736; Molecular function: L-fucose isomerase activity.

case <FT:3> and <FT:4> and <FT:5>
GO:0030145; Molecular function: manganese ion binding.
end case

GO:0006004; Biological process: fucose metabolic process.
GO:0005737; Cellular component: cytoplasm.
Features
From: FUCI_ECOLI (P69922)
Key     From     To       Description   Condition   FTGroup
ACT_SITE     337     337       Proton acceptor (By similarity)   E  
ACT_SITE     361     361       Proton acceptor (By similarity)   D  
METAL     337     337       Manganese (By similarity)   E  
METAL     361     361       Manganese (By similarity)   D  
METAL     528     528       Manganese (By similarity)   H  


Additional information

Size range: 582-595 amino acids
Related UniRules: None
Template: P69922 (FUCI_ECOLI)
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences