HAMAP annotation rule MF_01255
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Accession MF_01255
Dates 13-JAN-2005 (Created)
5-JAN-2012 (Last updated, Version 16)
Name Ectoine_synth
Scope Bacteria
Triggered by



Identifier
ECTC
Protein name
RecName: Full=L-ectoine synthase;
EC=4.2.1.108;
AltName: Full=N-acetyldiaminobutyrate dehydratase;
Gene name
ectC


FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity).
CATALYTIC ACTIVITY N(4)-acetyl-L-2,4-diaminobutanoate = L-ectoine + H(2)O.
PATHWAY Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde; step 3/3.
SIMILARITY Belongs to the ectoine synthase family.


Lyase


GO:0016836; Molecular function: hydro-lyase activity.
GO:0019491; Biological process: ectoine biosynthetic process.


Pfam PF06339; Ectoine_synth; 1;


Size range: 128-138 amino acids
Related Rules: None
Templates: O52251 (ECTC_HALED); O06061 (ECTC_MARHA); Q9AP33 (ECTC_BACPA): [Recover all]
Fusion: None
Comments: This protein is mainly found in halophilic bacteria, which synthesize ectoine as a good osmoprotectant.


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