HAMAP

Accession	MF_01255
Dates	13-JAN-2005 (Created) 22-OCT-2010 (Last updated, Version 15)

Data class

Protein

Predictors

HAMAP; MF_01255; [distribution of match scores in UniProtKB];[seed alignment for MF_01255]

Names

Ectoine_synth

Identifier

ECTC

Protein name

RecName: Full=L-ectoine synthase; EC=4.2.1.108; AltName: Full=N-acetyldiaminobutyrate dehydratase;

Gene name

ectC

FUNCTION: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity).

CATALYTIC ACTIVITY: N(4)-acetyl-L-2,4-diaminobutanoate = L-ectoine + H(2)O.

PATHWAY: Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 3/3.

SIMILARITY: Belongs to the ectoine synthase family.

Pfam	PF06339; Ectoine_synth; 1;

Lyase.

GO:0016836; Molecular function: hydro-lyase activity.
GO:0019491; Biological process: ectoine biosynthetic process.

Size range:	128-138 amino acids
Related UniRules:	None
Template:	O52251 (ECTC_HALED); O06061 (ECTC_MARHA); Q9AP33 (ECTC_BACPA): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	This protein is mainly found in halophilic bacteria, which synthesize ectoine as a good osmoprotectant.