Due to scheduled maintenance work, this service may not be available on Monday January 22nd between 08.00 am and 9.00 am CEST.
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Annotation rule MF_01265
Send feedback

General rule information [?]

Accession MF_01265
Dates 29-JUL-2005 (Created)
17-AUG-2016 (Last updated, Version 17)
Name NadX
Scope Bacteria; Proteobacteria
Bacteria; Thermotogae
Template Q9X1X6 (ASPD_THEMA)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Probable L-aspartate dehydrogenase;
Gene name

Comments [?]

Function Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
Catalytic activity L-aspartate + H(2)O + NAD(P)(+) = oxaloacetate + NH(3) + NAD(P)H.
Pathway Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1.
Miscellaneous The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.
Similarity Belongs to the L-aspartate dehydrogenase family.

Keywords [?]

Gene Ontology [?]

GO:0016639; Molecular function: oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor.
GO:0050661; Molecular function: NADP binding.
GO:0051287; Molecular function: NAD binding.
GO:0009435; Biological process: NAD biosynthetic process.

Cross-references [?]

Pfam PF01958; DUF108; 1;
PF03447; NAD_binding_3; 1;
TIGRFAMs TIGR03855; NAD_NadX; 1;

Features [?]

Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     193     193             H  
BINDING     109     109       NAD; via amide nitrogen     A  
BINDING     164     164       NAD     N  

Additional information [?]

Size range 236-280 amino acids
Related rules None
Fusion None