Annotation rule MF_01265
Send feedback

General rule information [?]

Accession MF_01265
Dates 29-JUL-2005 (Created)
6-JAN-2012 (Last updated, Version 15)
Name NadX
Scope Bacteria; Proteobacteria
Bacteria; Thermotogae
Archaea

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ASPD
Protein name
RecName: Full=Probable L-aspartate dehydrogenase;
EC=1.4.1.21;
Gene name
nadX

Comments [?]

Function Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity).
Catalytic activity L-aspartate + H(2)O + NAD(P)(+) = oxaloacetate + NH(3) + NAD(P)H.
Pathway Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route); step 1/1.
Miscellaneous The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia (By similarity).
Similarity Belongs to the L-aspartate dehydrogenase family.

Keywords [?]


Gene Ontology [?]

GO:0016639; Molecular function: oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor.
GO:0050661; Molecular function: NADP binding.
GO:0051287; Molecular function: NAD binding.
GO:0009435; Biological process: NAD biosynthetic process.

Cross-references [?]

Pfam PF01958; DUF108; 1;
PF03447; NAD_binding_3; 1;

Features [?]

From: ASPD_THEMA (Q9X1X6)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     193     193       By similarity     H  
BINDING     109     109       NAD; via amide nitrogen (By similarity)     A  
BINDING     164     164       NAD (By similarity)     N  

Additional information [?]

Size range 236-280 amino acids
Related rules None
Template Q9X1X6 (ASPD_THEMA)
Fusion None