HAMAP

Accession	MF_01270
Dates	31-AUG-2006 (Created) 7-JUL-2011 (Last updated, Version 12)

Data class

Protein

Predictors

HAMAP; MF_01270; [distribution of match scores in UniProtKB];[seed alignment for MF_01270]

Names

AnhMurNAc_kinase

Identifier

ANMK

Protein name

RecName: Full=Anhydro-N-acetylmuramic acid kinase; EC=2.7.1.170; AltName: Full=AnhMurNAc kinase;

Gene name

anmK

FUNCTION: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity).

CATALYTIC ACTIVITY: ATP + 1,6-anhydro-N-acetyl-beta-muramate + H(2)O = ADP + N-acetylmuramate 6-phosphate.

PATHWAY: Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.

PATHWAY: Cell wall biogenesis; peptidoglycan recycling.

SIMILARITY: Belongs to the anhydro-N-acetylmuramic acid kinase family.

Pfam	PF03702; UPF0075; 1;

ATP-binding, Carbohydrate metabolism, Kinase, Nucleotide-binding, Transferase.

GO:0005524; Molecular function: ATP binding.
GO:0016773; Molecular function: phosphotransferase activity, alcohol group as acceptor.
GO:0006040; Biological process: amino sugar metabolic process.
GO:0009254; Biological process: peptidoglycan turnover.

From: ANMK_ECOLI (P77570)
Key		From		To		Description		Condition		FTGroup
NP_BIND		12		19		ATP (Potential)

Size range:	355-436 amino acids
Related UniRules:	None
Template:	P77570 (ANMK_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in JANSC
Plasmid encoded:	in DEIGD