HAMAP

Accession	MF_01319
Dates	27-AUG-2003 (Created) 2-JUL-2010 (Last updated, Version 25)

Data class

Protein

Predictors

HAMAP; MF_01319; [distribution of match scores in UniProtKB];[seed alignment for MF_01319]

Names

ResA

Identifier

RESA

Protein name

RecName: Full=Thiol-disulfide oxidoreductase resA;

Gene name

resA

FUNCTION: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached (By similarity).

PATHWAY: Protein modification; cytochrome c assembly.

SUBCELLULAR LOCATION: Cell membrane; Single-pass type II membrane protein (By similarity). Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity).

SIMILARITY: Belongs to the thioredoxin family. ResA subfamily.

SIMILARITY: Contains 1 thioredoxin domain.

Pfam	PF00578; AhpC-TSA; 1;
PROSITE	PS00194; THIOREDOXIN_1; 1; PS51352; THIOREDOXIN_2; 1; trigger=PRU00691;

Cell membrane, Cytochrome c-type biogenesis.

Disulfide bond.

Membrane, Oxidoreductase, Redox-active center, Signal-anchor, Transmembrane, Transmembrane helix.

GO:0015036; Molecular function: disulfide oxidoreductase activity.
GO:0017004; Biological process: cytochrome complex assembly.
GO:0005886; Cellular component: plasma membrane.

From: RESA_BACSU (P35160)
Key		From		To		Description		Condition		FTGroup
TRANSMEM		11		30		Helical; Signal-anchor for type II membrane protein; (Potential)
DISULFID		74		77		Redox-active (By similarity)		C-x-P-C

Size range:	173-192 amino acids
Related UniRules:	None
Template:	P35160 (RESA_BACSU)
Scope:	Bacteria; Bacillaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None