HAMAP rule MF_01320
General rule information
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| Accession | MF_01320 |
| Dates | 2-FEB-2004 (Created)
22-SEP-2023 (Last updated, Version 30) |
| Name | Ribosomal_uL2 |
| Scope(s) |
Bacteria Archaea Plastid |
| Template(s) | Q9RXJ9 (RL2_DEIRA); P20276 (RL2_HALMA); P60422 (RL2_ECOLI); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01320_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_01320_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RL2 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL2; |
| Gene name | Name=rplB; |
| end case | |
| case <OC:Cyanobacteriota> | |
| Identifier | RL2 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL2; |
| Gene name | Name=rplB; Synonyms=rpl2; |
| end case | |
| case <OC:Archaea> | |
| Identifier | RL2 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL2; |
| Gene name | Name=rpl2; |
| end case | |
| case <OG:Chloroplast> | |
| Identifier | RK2 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL2c; |
| Gene name | Name=rpl2; |
| end case | |
Comments
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| case not <OG:Chloroplast> | |
| FUNCTION | One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. |
| SUBUNIT | Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. |
| end case | |
| case <OG:Chloroplast> | |
| SUBUNIT | Part of the 50S ribosomal subunit. |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the universal ribosomal protein uL2 family. |
Keywords
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| case <FT:1> | |
| Acetylation | |
| end case | |
| Ribonucleoprotein | |
| Ribosomal protein | |
| case not <OG:Chloroplast> | |
| RNA-binding | |
| rRNA-binding | |
| end case | |
Gene Ontology
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| GO:0019843; Molecular function:rRNA binding | |
| GO:0006412; Biological process:translation | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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| Pfam | PF00181; Ribosomal_L2; 1; |
| Pfam | PF03947; Ribosomal_L2_C; 1; |
| NCBIfam | TIGR01171; RplB_bact; 1; |
| PROSITE | PS00467; RIBOSOMAL_L2; 1; |
Features
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| From: RL2_ECOLI (P60422) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Escherichia> or <OC:Shigella> | ||||||||||||
| MOD_RES | 242 | 242 | /note="N6-acetyllysine" | K | ||||||||
| end case | ||||||||||||
Additional information
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| Size range | 233-304 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | The initiation codon is created by RNA editing in barley and maize, and is suggested to be created by editing in wheat. The same start codon exists in rice (ACG), so we suggest it too is edited. |