HAMAP rule MF_01331
General rule information
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| Accession | MF_01331 |
| Dates | 1-JUL-2004 (Created)
22-SEP-2023 (Last updated, Version 30) |
| Name | Ribosomal_uL22 |
| Scope(s) |
Bacteria Archaea Plastid |
| Template(s) | Q9RXJ7 (RL22_DEIRA); P61175 (RL22_ECOLI); P48286 (RL22_THETH); Q5SHP3 (RL22_THET8); P10970 (RL22_HALMA); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01331_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_01331_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RL22 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL22; |
| Gene name | Name=rplV; |
| else case <OC:Cyanobacteriota> | |
| Identifier | RL22 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL22; |
| Gene name | Name=rplV; Synonyms=rpl22; |
| else case <OC:Archaea> | |
| Identifier | RL22 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL22; |
| Gene name | Name=rpl22; |
| else case <OG:Chloroplast> | |
| Identifier | RK22 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL22c; |
| Gene name | Name=rpl22; |
| end case | |
Comments
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| case <OC:Bacteria> | |
| FUNCTION | This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. |
| else case <OC:Archaea> | |
| FUNCTION | This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. |
| else case <OG:Chloroplast> | |
| FUNCTION | This protein binds specifically to 23S rRNA. |
| end case | |
| FUNCTION | The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. |
| SUBUNIT | Part of the 50S ribosomal subunit. |
| case <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the universal ribosomal protein uL22 family. |
Keywords
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Gene Ontology
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| GO:0019843; Molecular function:rRNA binding | |
| GO:0006412; Biological process:translation | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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| Pfam | PF00237; Ribosomal_L22; 1; |
| NCBIfam | TIGR01044; RplV_bact; 1; |
| NCBIfam | TIGR01038; L22_arch; 1; |
| PROSITE | PS00464; RIBOSOMAL_L22; 1; |
Features
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Additional information
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| Size range | 148-185 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: <Unknown> |
| Comments | C-terminal fusion to an unknown domain in ACIC1, UREPA, UREP2. Plastid-encoded in most land plants; however it is nuclearly encoded in the Fabaceae. |