HAMAP rule MF_01347
General rule information
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| Accession | MF_01347 |
| Dates | 18-MAY-2006 (Created)
1-JUN-2023 (Last updated, Version 53) |
| Name | ATP_synth_beta_bact |
| Scope(s) |
Bacteria Plastid |
| Template(s) | P0ABB4 (ATPB_ECOLI); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01347 (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ATPB |
| case <OC:Bacteria> | |
| Protein name | RecName: Full=ATP synthase subunit beta; EC=7.1.2.2; AltName: Full=ATP synthase F1 sector subunit beta; AltName: Full=F-ATPase subunit beta; |
| else case <OG:Chloroplast> | |
| Protein name | RecName: Full=ATP synthase subunit beta, chloroplastic; EC=7.1.2.2; AltName: Full=ATP synthase F1 sector subunit beta; AltName: Full=F-ATPase subunit beta; |
| end case | |
| case <OG:Chloroplast> | |
| Gene name | Name=atpB; |
| else case <OC:Cyanobacteriota> | |
| Gene name | Name=atpD; Synonyms=atpB; |
| else | |
| Gene name | Name=atpD; |
| end case | |
Comments
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| FUNCTION | Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. |
| CATALYTIC ACTIVITY | Reaction=ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate; Xref=Rhea:RHEA:57720, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.1.2.2; |
| case <OG:Chloroplast> or <Property:PHOTOSYN> | |
| SUBUNIT | F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12). |
| else | |
| SUBUNIT | F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains. |
| end case | |
| case <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Plastid, chloroplast thylakoid membrane; Peripheral membrane protein. |
| else case <OC:Cyanobacteriota> and not <OC:Gloeobacter> | |
| SUBCELLULAR LOCATION | Cellular thylakoid membrane; Peripheral membrane protein. |
| else case <OC:Gloeobacter> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein. |
| else case not defined <Property:Membrane> or <Property:Membrane=1> | |
| SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein. |
| else case <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein. |
| end case | |
| SIMILARITY | Belongs to the ATPase alpha/beta chains family. |
Keywords
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| ATP synthesis | |
| ATP-binding | |
| CF(1) | |
| Hydrogen ion transport | |
| Ion transport | |
| Nucleotide-binding | |
| <a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a> | |
| Transport | |
| Membrane | |
| case <OG:Chloroplast> or <OC:Cyanobacteriota> and not <OC:Gloeobacter> | |
| Thylakoid | |
| else case <OC:Gloeobacter> | |
| Cell membrane | |
| Cell inner membrane | |
| else case not defined <Property:Membrane> or <Property:Membrane=1> | |
| Cell membrane | |
| else case <Property:Membrane=2> | |
| Cell membrane | |
| Cell inner membrane | |
| end case | |
Gene Ontology
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| GO:0005524; Molecular function:ATP binding | |
| GO:0046933; Molecular function:proton-transporting ATP synthase activity, rotational mechanism | |
| GO:0015986; Biological process:proton motive force-driven ATP synthesis | |
| case <OCellular component:Cyanobacteriota> and not <OC:Gloeobacter> | |
| GO:0042651; Cellular component:thylakoid membrane | |
| else case <OG:Chloroplast> | |
| GO:0009535; Cellular component:chloroplast thylakoid membrane | |
| else; https://www.ebi.ac.uk/QuickGO/term/else | |
| GO:0005886; Cellular component:plasma membrane | |
| end case | |
Cross-references
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| PROSITE | PS00152; ATPASE_ALPHA_BETA; 1; |
| Pfam | PF00006; ATP-synt_ab; 1; |
| Pfam | PF00306; ATP-synt_ab_C; 1; |
| Pfam | PF02874; ATP-synt_ab_N; 1; |
| NCBIfam | TIGR01039; AtpD; 1; |
Features
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| From: ATPB_ECOLI (P0ABB4) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 150 | 157 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
G-G-A-G-[V,L,C,M]-G-K-[T,S] | ||||||||
Additional information
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| Size range | 447-542 amino acids |
| Related rules |
None |
| Fusion | Nter: <Unknown> Cter: None |
| Comments | Fused with an unknown domain in MALP2. Some of the Rhizobiales have a slightly longer N-terminus. |