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HAMAP annotation rule: MF_01347
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General rule information

Accession MF_01347
Dates 18-MAY-2006 (Created)
18-AUG-2010 (Last updated, Version 27)
Data class Protein
Predictors HAMAP; MF_01347; [distribution of match scores in UniProtKB];[seed alignment for MF_01347]
Names ATP_synth_beta_bact


Propagated annotation

Identifier, protein and gene names
Identifier ATPB

case <OC:Bacteria>
Protein name
RecName: Full=ATP synthase subunit beta;
EC=3.6.3.14;
AltName: Full=ATP synthase F1 sector subunit beta;
AltName: Full=F-ATPase subunit beta;

else case <OG:Chloroplast>
Protein name
RecName: Full=ATP synthase subunit beta, chloroplastic;
EC=3.6.3.14;
AltName: Full=ATP synthase F1 sector subunit beta;
AltName: Full=F-ATPase subunit beta;
end case


case <OG:Chloroplast>
Gene name atpB

else case <OC:Cyanobacteria>
Gene name atpD, atpB

else
Gene name atpD
end case

Comments
FUNCTION: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity).
CATALYTIC ACTIVITY: ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).

case <OG:Chloroplast> or <Property:PHOTOSYN>
SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12) (By similarity).

else
SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).
end case


case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane; Peripheral membrane protein (By similarity).

else case <OC:Cyanobacteria> and not <OC:Gloeobacter>
SUBCELLULAR LOCATION: Cellular thylakoid membrane; Peripheral membrane protein (By similarity).

else case <OC:Gloeobacter>
SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein (By similarity).

else case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein (By similarity).

else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein (By similarity).
end case

SIMILARITY: Belongs to the ATPase alpha/beta chains family.
Cross-references
PROSITE PS00152; ATPASE_ALPHA_BETA; 1;
Pfam PF00006; ATP-synt_ab; 1;
PF00306; ATP-synt_ab_C; 1;
PF02874; ATP-synt_ab_N; 1;
TIGRFAMs TIGR01039; atpD; 1;
Keywords
ATP synthesis, ATP-binding, CF(1), Hydrogen ion transport, Hydrolase, Ion transport, Nucleotide-binding, Transport, Membrane.

case <OG:Chloroplast> or <OC:Cyanobacteria> and not <OC:Gloeobacter>
Thylakoid.

else case <OC:Gloeobacter>
Cell membrane, Cell inner membrane.

else case not defined <Property:Membrane> or <Property:Membrane=1>
Cell membrane.

else case <Property:Membrane=2>
Cell membrane, Cell inner membrane.
end case

Gene Ontology
GO:0005524; Molecular function: ATP binding.
GO:0046933; Molecular function: hydrogen ion transporting ATP synthase activity, rotational mechanism.
GO:0042777; Biological process: plasma membrane ATP synthesis coupled proton transport.

case <OC:Cyanobacteria> and not <OC:Gloeobacter>
GO:0042651; Cellular component: thylakoid membrane.

else case <OG:Chloroplast>
GO:0009535; Cellular component: chloroplast thylakoid membrane.

else
GO:0005886; Cellular component: plasma membrane.
end case

Features
From: ATPB_ECOLI (P0ABB4)
Key     From     To       Description   Condition   FTGroup
NP_BIND     150     157       ATP (By similarity)   G-G-A-G-[V,L,C,M]-G-K-[T,S]  


Additional information

Size range: 447-542 amino acids
Related UniRules: None
Template: P0ABB4 (ATPB_ECOLI)
Scope: Bacteria
Plastid
Fusion: Nter: <Unknown>; Cter: None
Duplicate: in BRASB, BURM7, BURMA, BURMS, BURP0, BURP1, BURP6, BURPS, BURXL, CHLTE, DINSH, GLUOX, LISIN, LISMF, LISMO, LISW6, MARMS, MYCPU, NITEC, NITMU, PELCD, PELLD, PELPD, PHOPR, POLNA, PSEA6, PSYIN, RHOFD, RHOS1, SHEFN, VIBHB
Plasmid encoded: in RHOS1, RHOS4
Comments: Fused with an unknown domain in MYCPE. Some of the Rhizobiales have a slightly longer N-terminus.

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UniProtKB rule member sequences