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HAMAP rule MF_01347

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General rule information [?]

Accession MF_01347
Dates 18-MAY-2006 (Created)
1-JUN-2023 (Last updated, Version 53)
Name ATP_synth_beta_bact
Scope(s) Bacteria
Plastid
Template(s) P0ABB4 (ATPB_ECOLI); [ Recover all ]
Triggered by
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01347 (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ATPB
case <OC:Bacteria>
Protein name RecName: Full=ATP synthase subunit beta;
                 EC=7.1.2.2;
AltName: Full=ATP synthase F1 sector subunit beta;
AltName: Full=F-ATPase subunit beta;
else case <OG:Chloroplast>
Protein name RecName: Full=ATP synthase subunit beta, chloroplastic;
                 EC=7.1.2.2;
AltName: Full=ATP synthase F1 sector subunit beta;
AltName: Full=F-ATPase subunit beta;
end case
case <OG:Chloroplast>
Gene name Name=atpB;
else case <OC:Cyanobacteriota>
Gene name Name=atpD; Synonyms=atpB;
else
Gene name Name=atpD;
end case

Comments [?]

FUNCTIONProduces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
CATALYTIC ACTIVITY Reaction=ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate; Xref=Rhea:RHEA:57720, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.1.2.2;
case <OG:Chloroplast> or <Property:PHOTOSYN>
SUBUNITF-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
else
SUBUNITF-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
end case
case <OG:Chloroplast>
SUBCELLULAR LOCATIONPlastid, chloroplast thylakoid membrane; Peripheral membrane protein.
else case <OC:Cyanobacteriota> and not <OC:Gloeobacter>
SUBCELLULAR LOCATIONCellular thylakoid membrane; Peripheral membrane protein.
else case <OC:Gloeobacter>
SUBCELLULAR LOCATIONCell inner membrane; Peripheral membrane protein.
else case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Peripheral membrane protein.
end case
SIMILARITYBelongs to the ATPase alpha/beta chains family.

Keywords [?]

ATP synthesis
ATP-binding
CF(1)
Hydrogen ion transport
Ion transport
Nucleotide-binding
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>
Transport
Membrane
case <OG:Chloroplast> or <OC:Cyanobacteriota> and not <OC:Gloeobacter>
Thylakoid
else case <OC:Gloeobacter>
Cell membrane
Cell inner membrane
else case not defined <Property:Membrane> or <Property:Membrane=1>
Cell membrane
else case <Property:Membrane=2>
Cell membrane
Cell inner membrane
end case

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0046933; Molecular function:proton-transporting ATP synthase activity, rotational mechanism
GO:0015986; Biological process:proton motive force-driven ATP synthesis
case <OCellular component:Cyanobacteriota> and not <OC:Gloeobacter>
GO:0042651; Cellular component:thylakoid membrane
else case <OG:Chloroplast>
GO:0009535; Cellular component:chloroplast thylakoid membrane
else; https://www.ebi.ac.uk/QuickGO/term/else
GO:0005886; Cellular component:plasma membrane
end case

Cross-references [?]

PROSITE PS00152; ATPASE_ALPHA_BETA; 1;
Pfam PF00006; ATP-synt_ab; 1;
Pfam PF00306; ATP-synt_ab_C; 1;
Pfam PF02874; ATP-synt_ab_N; 1;
NCBIfam TIGR01039; AtpD; 1;

Features [?]

From: ATPB_ECOLI (P0ABB4)
Key From To Description Tag Condition FTGroup
BINDING 150 157 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
G-G-A-G-[V,L,C,M]-G-K-[T,S]

Additional information [?]

Size range 447-542 amino acids
Related rules None
Fusion Nter: <Unknown> Cter: None
Comments Fused with an unknown domain in MALP2. Some of the Rhizobiales have a slightly longer N-terminus.



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