HAMAP

Accession	MF_01377
Dates	4-JUN-2007 (Created) 21-JAN-2011 (Last updated, Version 14)

Data class

Protein

Predictors

HAMAP; MF_01377; [distribution of match scores in UniProtKB];[seed alignment for MF_01377]

Names

YegS

Identifier

YEGS

Protein name

RecName: Full=Probable lipid kinase YegS; EC=2.7.1.-;

Gene name

yegS

Protein name

RecName: Full=Probable lipid kinase YegS-like; EC=2.7.1.-;

FUNCTION: Probably phosphorylates lipids; the in vivo substrate is unknown (By similarity).

COFACTOR: Binds 1 magnesium ion per subunit. Calcium may be able to substitute (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.

Pfam	PF00781; DAGK_cat; 1;
TIGRFAMs	TIGR00147; CHP147; 1;
PROSITE	PS50146; DAGK; 1; trigger=PRU00783;

ATP-binding, Cytoplasm, Kinase, Magnesium, Metal-binding, Nucleotide-binding, Phospholipid biosynthesis, Transferase.

GO:0000287; Molecular function: magnesium ion binding.
GO:0001727; Molecular function: lipid kinase activity.
GO:0005524; Molecular function: ATP binding.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

From: YEGS_ECOLI (P76407)
Key		From		To		Description		Condition		FTGroup
NP_BIND		66		72		ATP (By similarity)
ACT_SITE		271		271		Proton acceptor (By similarity)		E
METAL		215		215		Magnesium; via carbonyl oxygen (By similarity)		[LVKRM]
METAL		218		218		Magnesium (By similarity)		D
METAL		220		220		Magnesium; via carbonyl oxygen (By similarity)		L
BINDING		40		40		ATP (By similarity)		[TS]
BINDING		95		95		ATP (By similarity)		[TS]

Size range:	295-311 amino acids
Related UniRules:	None
Template:	P76407 (YEGS_ECOLI); Q8ZNP1 (YEGS_SALTY): [Recover all]
Scope:	Bacteria; Gammaproteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None