HAMAP rule MF_01389
General rule information
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| Accession | MF_01389 |
| Dates | 24-JUL-2008 (Created)
1-JUN-2023 (Last updated, Version 16) |
| Name | UreG |
| Scope(s) |
Bacteria Actinomycetota Bacteroidota Chloroflexota Cyanobacteriota Deinococcota Bacillota Pseudomonadota Magnetococcus Verrucomicrobiota Archaea |
| Template(s) | P18319 (UREG_KLEAE); P9WFE3 (UREG_MYCTU); Q9RP19 (UREG_SPOPA); Q09066 (UREG_HELPY); [ Recover all ] |
| Triggered by |
HAMAP; MF_01389 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | UREG |
| Protein name | RecName: Full=Urease accessory protein UreG; |
| Gene name | Name=ureG; |
Comments
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| FUNCTION | Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. |
| case not <OC:Helicobacter> | |
| SUBUNIT | Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. |
| else case <OC:Helicobacter> | |
| SUBUNIT | Homodimer. UreH, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. |
| end case | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the SIMIBI class G3E GTPase family. UreG subfamily. |
Keywords
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Gene Ontology
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| GO:0016151; Molecular function:nickel cation binding |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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| From: UREG_HELPY (Q09066) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 8 | 15 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
[GA]-[PR]-[VW]-[GA]-[STAP]-[GA]-[KR]-[TSHRM] | ||||||||
Additional information
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| Size range | 195-250 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | SORC5 has a long N-terminus, not used in size range. |