HAMAP

Accession	MF_01389
Dates	24-JUL-2008 (Created) 19-SEP-2011 (Last updated, Version 4)

Data class

Protein

Predictors

HAMAP; MF_01389; [distribution of match scores in UniProtKB];[seed alignment for MF_01389]

Names

UreG

Identifier

UREG

Protein name

RecName: Full=Urease accessory protein UreG;

Gene name

ureG

FUNCTION: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity).

SUBUNIT: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel (By similarity).

SUBUNIT: Homodimer. UreH, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the UreG family.

Pfam	PF02492; cobW; 1;
TIGRFAMs	TIGR00101; UreG; 1;

Chaperone, Cytoplasm, GTP-binding, Nickel insertion, Nucleotide-binding.

GO:0016151; Molecular function: nickel ion binding.
GO:0005737; Cellular component: cytoplasm.

From: UREG_HELPY (Q09066)
Key		From		To		Description		Condition		FTGroup
NP_BIND		8		15		GTP (By similarity)		[GA]-[PR]-[VW]-[GA]-[STAP]-[GA]-[KR]-[TSHRM]

Size range:	195-250 amino acids
Related UniRules:	None
Template:	P18319 (UREG_ENTAE); P0A664 (UREG_MYCTU); Q9RP19 (UREG_BACPA); Q09066 (UREG_HELPY): [Recover all]
Scope:	Bacteria; Actinobacteria Bacteria; Bacteroidetes Bacteria; Chloroflexi Bacteria; Cyanobacteria Bacteria; Deinococcus-Thermus Bacteria; Firmicutes Bacteria; Proteobacteria Bacteria; Magnetococcus Bacteria; Verrucomicrobia Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	in BRASB, BRUA2, BRUAB, BRUSU, BURMA, BURPS, ECO57, METEP, SACEN, STRGG
Plasmid encoded:	in ECOLX, HALMA, METRJ
Comments:	SORC5 has a long N-terminus, not used in size range.