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HAMAP rule MF_01389

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General rule information [?]

Accession MF_01389
Dates 24-JUL-2008 (Created)
1-JUN-2023 (Last updated, Version 16)
Name UreG
Scope(s) Bacteria
Actinomycetota
Bacteroidota
Chloroflexota
Cyanobacteriota
Deinococcota
Bacillota
Pseudomonadota
Magnetococcus
Verrucomicrobiota
Archaea
Template(s) P18319 (UREG_KLEAE); P9WFE3 (UREG_MYCTU); Q9RP19 (UREG_SPOPA); Q09066 (UREG_HELPY); [ Recover all ]
Triggered by HAMAP; MF_01389 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier UREG
Protein name RecName: Full=Urease accessory protein UreG;
Gene name Name=ureG;

Comments [?]

FUNCTIONFacilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
case not <OC:Helicobacter>
SUBUNITHomodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.
else case <OC:Helicobacter>
SUBUNITHomodimer. UreH, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.
end case
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the SIMIBI class G3E GTPase family. UreG subfamily.

Keywords [?]


Gene Ontology [?]

GO:0016151; Molecular function:nickel cation binding
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02492; cobW; 1;
NCBIfam TIGR00101; UreG; 1;

Features [?]

From: UREG_HELPY (Q09066)
Key From To Description Tag Condition FTGroup
BINDING 8 15 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
[GA]-[PR]-[VW]-[GA]-[STAP]-[GA]-[KR]-[TSHRM]

Additional information [?]

Size range 195-250 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments SORC5 has a long N-terminus, not used in size range.



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