Annotation rule MF_01398
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General rule information [?]

Accession MF_01398
Dates 9-MAR-2009 (Created)
28-APR-2014 (Last updated, Version 17)
Name ATP_synth_b_bact
Scope Bacteria
Plastid

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ATPF
case <OC:Bacteria>
Protein name
RecName: Full=ATP synthase subunit b;
AltName: Full=ATP synthase F(0) sector subunit b;
AltName: Full=ATPase subunit I;
AltName: Full=F-type ATPase subunit b;
Short=F-ATPase subunit b;
else case <OG:Chloroplast>
Protein name
RecName: Full=ATP synthase subunit b, chloroplastic;
AltName: Full=ATP synthase F(0) sector subunit b;
AltName: Full=ATPase subunit I;
end case
Gene name
atpF

Comments [?]

Function F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity).
case <OG:Chloroplast> or <OC:Cyanobacteria>
Subunit F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains (By similarity).
else
Subunit F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).
end case
case <OG:Chloroplast>
Subcellular location Plastid, chloroplast thylakoid membrane; Single-pass membrane protein (By similarity).
else case <OC:Cyanobacteria> and not <OC:Gloeobacter>
Subcellular location Cellular thylakoid membrane; Single-pass membrane protein (By similarity).
else case <OC:Gloeobacter>
Subcellular location Cell inner membrane; Single-pass membrane protein (By similarity).
else case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Single-pass membrane protein (By similarity).
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Single-pass membrane protein (By similarity).
end case
case <OG:Chloroplast>
Miscellaneous In plastids the F-type ATPase is also known as CF(1)CF(0).
end case
Similarity Belongs to the ATPase B chain family.

Keywords [?]

case <OG:Chloroplast> or <OC:Cyanobacteria> and not <OC:Gloeobacter>
else case <OC:Gloeobacter>
else case not defined <Property:Membrane> or <Property:Membrane=1>
else case <Property:Membrane=2>
end case

Gene Ontology [?]

GO:0046933; Molecular function: proton-transporting ATP synthase activity, rotational mechanism.
case <OC:Cyanobacteria> and not <OC:Gloeobacter>
GO:0042651; Cellular component: thylakoid membrane.
else case <OG:Chloroplast>
GO:0009535; Cellular component: chloroplast thylakoid membrane.
else
GO:0042777; Biological process: plasma membrane ATP synthesis coupled proton transport.
GO:0005886; Cellular component: plasma membrane.
end case

Cross-references [?]

Pfam PF00430; ATP-synt_B; 1;
TIGRFAMs TIGR01144; ATP_synt_b; 1;

Computed features [?]

General Transmembrane; -; 1; trigger=yes;

Additional information [?]

Size range 143-326 amino acids
Related rules MF_01399 (ATPX supersedes the current rule)
Templates P0ABA0 (ATPF_ECOLI); P09221 (ATPF_BACP3); Q0ZS23 (ATPF_CLOPD); Q2RFX5 (ATPF_MOOTA); O05333 (ATPF_RHOCA): [Recover all]
Fusion Nter: None; Cter: MF_01416 (atpD)
Comments This family includes potential copies of the b' subunit in non- cyanobacteria; however all are now called subunit b. Quite a few non-model bacteria have more than 1 copy of this protein, including potential copies of the b' subunit; exactly which copies are found in the enzyme requires more study. In Mycoplasma pneumoniae (ATCC 29342 / M129) this is a lipoprotein; this is suggested for similar Mycoplasmataceae. Sometimes predicted to have 2 transmembrane helices. In some of the Mycobacteria one copy is fused with the delta subunit. Some have a longer C-terminus. For a review on the peripheral (stator) stalk see PubMed=16730323; DOI=10.1016/j.bbabio.2006.04.007; Weber J.; "ATP synthase: subunit-subunit interactions in the stator stalk."; Biochim. Biophys. Acta 1757:1162-1170(2006).