HAMAP

Accession	MF_01411
Dates	6-NOV-2002 (Created) 8-JUN-2010 (Last updated, Version 28)

Data class

Protein

Predictors

HAMAP; MF_01411; [distribution of match scores in UniProtKB];[seed alignment for MF_01411]

Names

OstA

Identifier

LPTD

Protein name

RecName: Full=LPS-assembly protein lptD; AltName: Full=Organic solvent tolerance protein; Flags: Precursor;

Gene name

lptD, ostA

FUNCTION: Together with lptE, is involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity).

SUBUNIT: Forms a high-molecular-weight complex in the outer membrane. Interacts with lptE (By similarity).

FUNCTION: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity).

SUBUNIT: Forms a high-molecular-weight complex in the outer membrane (By similarity).

SUBCELLULAR LOCATION: Cell outer membrane (By similarity).

PTM: Forms at least two disulfide bridges, one inter- and one intramolecular (By similarity).

SIMILARITY: Belongs to the lptD family.

Pfam	PF03968; OstA; 1;
General	Signal; -; 1; trigger=Yes;

Cell membrane, Cell outer membrane.

Disulfide bond.

Membrane, Signal.

GO:0043165; Biological process: Gram-negative-bacterium-type cell outer membrane assembly.
GO:0009279; Cellular component: cell outer membrane.

Size range:	723-945 amino acids
Related UniRules:	None
Template:	P31554 (LPTD_ECOLI)
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	PSEAE lptD is highly divergent