HAMAP

Accession	MF_01418
Dates	5-MAR-2004 (Created) 2-DEC-2011 (Last updated, Version 15)

Data class

Protein

Predictors

HAMAP; MF_01418; [distribution of match scores in UniProtKB];[seed alignment for MF_01418]

Names

SpeB

Identifier

SPEB

Protein name

RecName: Full=Agmatinase; EC=3.5.3.11; AltName: Full=Agmatine ureohydrolase; Short=AUH;

Gene name

speB

FUNCTION: Catalyzes the formation of putrescine from agmatine (By similarity).

CATALYTIC ACTIVITY: Agmatine + H(2)O = putrescine + urea.

COFACTOR: Manganese (By similarity).

PATHWAY: Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine: step 1/1.

SIMILARITY: Belongs to the arginase family. Agmatinase subfamily.

Pfam	PF00491; Arginase; 1;
TIGRFAMs	TIGR01230; Agmatinase; 1;
PROSITE	PS01053; ARGINASE_1; 1; PS51409; ARGINASE_2; 1;

Polyamine biosynthesis, Spermidine biosynthesis, Putrescine biosynthesis, Hydrolase, Metal-binding, Manganese.

GO:0008783; Molecular function: agmatinase activity.
GO:0009446; Biological process: putrescine biosynthetic process.
GO:0008295; Biological process: spermidine biosynthetic process.

From: SPEB_ECOLI (P60651)
Key		From		To		Description		Condition		FTGroup
METAL		126		126		Manganese (By similarity)		H
METAL		149		149		Manganese (By similarity)		D
METAL		151		151		Manganese (By similarity)		H
METAL		153		153		Manganese (By similarity)		D
METAL		230		230		Manganese (By similarity)		D
METAL		232		232		Manganese (By similarity)		D

Size range:	303-322 amino acids
Related UniRules:	None
Template:	P60651 (SPEB_ECOLI)
Scope:	Bacteria; Neisseriales Bacteria; Enterobacteriales
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	This protein has not been found in Yersinia pestis.