HAMAP rule MF_01419
General rule information
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| Accession | MF_01419 |
| Dates | 15-MAR-2004 (Created)
1-JUN-2023 (Last updated, Version 19) |
| Name | GPH_hydrolase_arch |
| Scope(s) |
Archaea |
| Template(s) | Q9HLQ2 (PGP_THEAC); [ Recover all ] |
| Triggered by |
HAMAP; MF_01419 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PGP |
| Protein name | RecName: Full=Phosphoglycolate phosphatase; Short=PGP; Short=PGPase; EC=3.1.3.18; |
Comments
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| FUNCTION | Catalyzes the dephosphorylation of 2-phosphoglycolate. |
| CATALYTIC ACTIVITY | Reaction=2-phosphoglycolate + H2O = glycolate + phosphate; Xref=Rhea:RHEA:14369, ChEBI:CHEBI:15377, ChEBI:CHEBI:29805, ChEBI:CHEBI:43474, ChEBI:CHEBI:58033; EC=3.1.3.18; |
| COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; |
| SIMILARITY | Belongs to the archaeal SPP-like hydrolase family. |
Keywords
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Gene Ontology
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| GO:0008967; Molecular function:phosphoglycolate phosphatase activity |
Cross-references
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| Pfam | PF00702; Hydrolase; 1; |
| NCBIfam | TIGR01484; HAD-SF-IIB; 1; |
| NCBIfam | TIGR01487; SPP-like; 1; |
| NCBIfam | TIGR01482; SPP-subfamily; 1; |
Features
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| From: PGP_THEAC (Q9HLQ2) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 8 | 8 | /note="Nucleophile" | D | ||||||||
| BINDING | 8 | 8 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | ||||||||
| BINDING | 10 | 10 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | ||||||||
| BINDING | 174 | 174 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | ||||||||
| BINDING | 178 | 178 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | ||||||||
| BINDING | 151 | 151 | /ligand="substrate" | K | ||||||||
Additional information
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| Size range | 221-239 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |