HAMAP

Accession	MF_01422
Dates	2-FEB-2005 (Created) 7-OCT-2011 (Last updated, Version 14)

Data class

Protein

Predictors

HAMAP; MF_01422; [distribution of match scores in UniProtKB];[seed alignment for MF_01422]

Names

MdtA

Identifier

MDTA

Protein name

RecName: Full=Multidrug resistance protein MdtA; AltName: Full=Multidrug transporter MdtA; Flags: Precursor;

Gene name

mdtA

FUNCTION: The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate (By similarity).

SUBUNIT: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC (By similarity).

SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein (Potential).

INDUCTION: The mdtABC operon is transcriptionally activated by BaeR.

SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

Pfam	PF00529; HlyD; 1;
TIGRFAMs	TIGR01730; RND_mfp; 1;
General	Signal; -; 1; trigger=Yes;

Cell membrane, Cell inner membrane, Membrane, Transport.

GO:0005215; Molecular function: transporter activity.
GO:0005886; Cellular component: plasma membrane.

Size range:	401-444 amino acids
Related UniRules:	None
Template:	P76397 (MDTA_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	The sequence of Shigella flexneri is shorter but it is impossible to correct the sequence.