Annotation rule MF_01423
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General rule information [?]

Accession MF_01423
Dates 2-FEB-2005 (Created)
11-OCT-2011 (Last updated, Version 17)
Name MdtB
Scope Bacteria; Enterobacteriaceae

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MDTB
Protein name
RecName: Full=Multidrug resistance protein MdtB;
AltName: Full=Multidrug transporter MdtB;
Gene name
mdtB

Comments [?]

case <OC:Escherichia>
Function The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate (By similarity).
end case
Subunit Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC (By similarity).
Subcellular location Cell inner membrane; Multi-pass membrane protein (Potential).
case <OC:Escherichia>
Induction The mdtABC operon is transcriptionally activated by BaeR.
end case
Similarity Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family.

Keywords [?]


Gene Ontology [?]

GO:0005215; Molecular function: transporter activity.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF00873; ACR_tran; 1;
PRINTS PR00702; ACRIFLAVINRP; 1;

Computed features [?]

General Transmembrane; -; 11-12; trigger=yes;

Additional information [?]

Size range 1039-1056 amino acids
Related rules None
Template P76398 (MDTB_ECOLI)
Fusion None
Comments The complete proteome of Shigella flexneri strain 301 does not contain mdtB. The sequence contains an in-frame codon. The authors have checked the sequence and is believed to be correct.