HAMAP

Accession	MF_01424
Dates	2-FEB-2005 (Created) 11-OCT-2011 (Last updated, Version 18)

Data class

Protein

Predictors

HAMAP; MF_01424; [distribution of match scores in UniProtKB];[seed alignment for MF_01424]

Names

MdtC

Identifier

MDTC

Protein name

RecName: Full=Multidrug resistance protein MdtC; AltName: Full=Multidrug transporter MdtC;

Gene name

mdtC

FUNCTION: The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate (By similarity).

SUBUNIT: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB (By similarity).

SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).

INDUCTION: The mdtABC operon is transcriptionally activated by BaeR.

SIMILARITY: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family.

Pfam	PF00873; ACR_tran; 1;
PRINTS	PR00702; ACRIFLAVINRP; 1;
General	Transmembrane; -; 10-12; trigger=Yes;

Cell membrane, Cell inner membrane, Membrane, Transport, Transmembrane, Transmembrane helix.

GO:0005215; Molecular function: transporter activity.
GO:0005886; Cellular component: plasma membrane.

Size range:	1021-1036 amino acids
Related UniRules:	None
Template:	P76399 (MDTC_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None