HAMAP

Accession	MF_01438
Dates	7-JUN-2006 (Created) 27-MAY-2011 (Last updated, Version 8)

Data class

Protein

Predictors

HAMAP; MF_01438; [distribution of match scores in UniProtKB];[seed alignment for MF_01438]

Names

DisA

Identifier

DISA

Protein name

RecName: Full=DNA integrity scanning protein DisA;

Gene name

disA

FUNCTION: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation (By similarity).

FUNCTION: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity).

SIMILARITY: Belongs to the DisA family.

Pfam	PF10635; DisA-linker; 1; PF02457; DisA_N; 1; PF00633; HHH; 1;

DNA damage, DNA repair, DNA-binding.

GO:0003677; Molecular function: DNA binding.
GO:0006281; Biological process: DNA repair.

Size range:	344-374 amino acids
Related UniRules:	None
Template:	P37573 (DISA_BACSU)
Scope:	Bacteria; Actinobacteria Bacteria; Bacillaceae Bacteria; Clostridiaceae Bacteria; Carboxydothermus Bacteria; Fusobacterium Bacteria; Thermotoga
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None