HAMAP rule MF_01523
General rule information
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| Accession | MF_01523 |
| Dates | 10-NOV-2004 (Created)
19-NOV-2022 (Last updated, Version 26) |
| Name | 16SrRNA_methyltr_J |
| Scope(s) |
Bacteria |
| Template(s) | P68567 (RSMJ_ECOLI); Q7UAV7 (RSMJ_SHIFL); [ Recover all ] |
| Triggered by |
HAMAP; MF_01523 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RSMJ |
| Protein name | RecName: Full=Ribosomal RNA small subunit methyltransferase J; EC=2.1.1.242; AltName: Full=16S rRNA m2G1516 methyltransferase; AltName: Full=rRNA (guanine-N(2)-)-methyltransferase; |
| Gene name | Name=rsmJ; |
Comments
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| FUNCTION | Specifically methylates the guanosine in position 1516 of 16S rRNA. |
| CATALYTIC ACTIVITY | Reaction=guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:43220, Rhea:RHEA-COMP:10412, Rhea:RHEA-COMP:10413, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.242; |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the methyltransferase superfamily. RsmJ family. |
Keywords
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Gene Ontology
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| GO:0008990; Molecular function:rRNA (guanine-N2-)-methyltransferase activity |
| GO:0031167; Biological process:rRNA methylation |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF04445; SAM_MT; 1; |
Features
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| From: RSMJ_SHIFL (Q7UAV7) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 101 | 102 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
R-[DE] | ||||||||
| BINDING | 117 | 118 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[ED]-R | ||||||||
| BINDING | 153 | 154 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
S-S | ||||||||
| BINDING | 171 | 171 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[DE] | ||||||||
Additional information
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| Size range | 200-296 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |