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HAMAP annotation rule: MF_01528
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General rule information

Accession MF_01528
Dates 4-FEB-2005 (Created)
1-NOV-2011 (Last updated, Version 25)
Data class Protein
Predictors HAMAP; MF_01528; [distribution of match scores in UniProtKB];[seed alignment for MF_01528]
Names MFS_MdtG


Propagated annotation

Identifier, protein and gene names
Identifier MDTG
Protein name
RecName: Full=Multidrug resistance protein MdtG;
Gene name mdtG
Comments

case <OC:Escherichia>
FUNCTION: Confers resistance to fosfomycin and deoxycholate (By similarity).
end case


case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (Potential).

else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (Potential).
end case

SIMILARITY: Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
Cross-references
Pfam PF07690; MFS_1; 1;
PRINTS PR01035; TCRTETA; 1;
PROSITE PS50850; MFS; 1;
General Transmembrane; -; 10-11; trigger=Yes;
Keywords

case <OC:Escherichia>
Antibiotic resistance.
end case

Cell membrane.

case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane.
end case

Membrane, Transmembrane, Transport, Transmembrane helix.
Gene Ontology
GO:0022857; Molecular function: transmembrane transporter activity.
GO:0055085; Biological process: transmembrane transport.
GO:0005887; Cellular component: integral to plasma membrane.


Additional information

Size range: 402-418 amino acids
Related UniRules: None
Template: P25744 (MDTG_ECOLI)
Scope: Bacteria; Enterobacteriaceae
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences