HAMAP

Accession	MF_01545
Dates	4-NOV-2005 (Created) 6-OCT-2011 (Last updated, Version 18)

Data class

Protein

Predictors

HAMAP; MF_01545; [distribution of match scores in UniProtKB];[seed alignment for MF_01545]

Names

AaeB

Identifier

AAEB

Protein name

RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB; Short=pHBA efflux pump protein B;

Gene name

aaeB

FUNCTION: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity).

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).

INDUCTION: Positively coregulated with aaeA and aaeX by AaeR (By similarity).

MISCELLANEOUS: Both AaeB and AaeA are required for the function of the efflux system (By similarity).

SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.

Pfam	PF04632; FUSC; 1;
General	Transmembrane; -; 11; trigger=Yes;

Cell membrane.

Cell inner membrane.

Membrane, Transmembrane, Transport, Transmembrane helix.

GO:0006810; Biological process: transport.
GO:0005886; Cellular component: plasma membrane.

Size range:	648-662 amino acids
Related UniRules:	None
Template:	P46481 (AAEB_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None