HAMAP rule MF_01554
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01554 |
| Accession | MF_01554 |
| Dates | 6-DEC-2005 (Created)
1-JUN-2023 (Last updated, Version 19) |
| Name | GlmM |
| Scope(s) |
Bacteria Archaea |
| Template(s) | P31120 (GLMM_ECOLI); Q5HE43 (GLMM_STAAC); P25177 (GLMM_HELPY); Q6LYB4 (GLMM_METMP); Q58500 (GLMM_METJA); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria>
HAMAP; MF_01554_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_01554_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| Identifier | GLMM |
| case <OC:Bacteria> or <OC:Methanococci> | |
| Protein name | RecName: Full=Phosphoglucosamine mutase; EC=5.4.2.10; |
| else | |
| Protein name | RecName: Full=Probable phosphoglucosamine mutase; EC=5.4.2.10; |
| end case | |
| Gene name | Name=glmM; |
Comments
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| FUNCTION | Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. |
| CATALYTIC ACTIVITY | Reaction=alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate; Xref=Rhea:RHEA:23424, ChEBI:CHEBI:58516, ChEBI:CHEBI:58725; EC=5.4.2.10; |
| case <FTGroup:1> | |
| COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Note=Binds 1 Mg(2+) ion per subunit.; |
| end case | |
| PTM | Activated by phosphorylation. |
| SIMILARITY | Belongs to the phosphohexose mutase family. |
Keywords
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| Isomerase | |
| case <FTGroup:1> | |
| Magnesium | |
| Metal-binding | |
| end case | |
| Phosphoprotein | |
Gene Ontology
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| GO:0008966; Molecular function:phosphoglucosamine mutase activity | |
| case <FTGroup:1> | |
| GO:0000287; Molecular function:magnesium ion binding | |
| end case | |
Cross-references
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| PROSITE | PS00710; PGM_PMM; 1; |
| Pfam | PF02878; PGM_PMM_I; 1; |
| Pfam | PF02879; PGM_PMM_II; 1; |
| Pfam | PF02880; PGM_PMM_III; 1; |
| Pfam | PF00408; PGM_PMM_IV; 1; |
| PRINTS | PR00509; PGMPMM; 1; |
| NCBIfam | TIGR01455; GlmM; 1; |
| NCBIfam | TIGR03990; Arch_GlmM; 1; |
Features
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| From: GLMM_ECOLI (P31120) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Bacteria> | ||||||||||||
| ACT_SITE | 102 | 102 | /note="Phosphoserine intermediate" | S | ||||||||
| BINDING | 102 | 102 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /note="via phosphate group" |
S | 1 | |||||||
| BINDING | 241 | 241 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | 1 | |||||||
| BINDING | 243 | 243 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | 1 | |||||||
| BINDING | 245 | 245 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | 1 | |||||||
| MOD_RES | 102 | 102 | /note="Phosphoserine" | S | ||||||||
| end case | ||||||||||||
| From: GLMM_METMP (Q6LYB4) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Archaea> | ||||||||||||
| ACT_SITE | 88 | 88 | /note="Phosphoserine intermediate" | S | ||||||||
| BINDING | 88 | 88 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /note="via phosphate group" |
S | 1 | |||||||
| BINDING | 231 | 231 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | 1 | |||||||
| BINDING | 233 | 233 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | 1 | |||||||
| BINDING | 235 | 235 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | 1 | |||||||
| MOD_RES | 88 | 88 | /note="Phosphoserine" | S | ||||||||
| end case | ||||||||||||
Additional information
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| Size range | 433-452 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |