HAMAP

Accession	MF_01558
Dates	12-DEC-2005 (Created) 2-DEC-2011 (Last updated, Version 8)

Data class

Protein

Predictors

HAMAP; MF_01558; [distribution of match scores in UniProtKB];[seed alignment for MF_01558]

Names

Cyt_deam

Identifier

CDD

Protein name

RecName: Full=Cytidine deaminase; EC=3.5.4.5; AltName: Full=Cytidine aminohydrolase; Short=CDA;

Gene name

cdd

FUNCTION: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity).

CATALYTIC ACTIVITY: Cytidine + H(2)O = uridine + NH(3).

COFACTOR: Binds 1 zinc ion (By similarity).

SUBUNIT: Homodimer (By similarity).

SIMILARITY: Belongs to the cytidine and deoxycytidylate deaminase family.

Pfam	PF00383; dCMP_cyt_deam_1; 1; PF08211; dCMP_cyt_deam_2; 1;
TIGRFAMs	TIGR01355; cyt_deam_dimer; 1;
PROSITE	PS00903; CYT_DCMP_DEAMINASES; 1;

Hydrolase.

Metal-binding, Zinc.

GO:0004126; Molecular function: cytidine deaminase activity.

GO:0008270; Molecular function: zinc ion binding.

From: CDD_ECOLI (P0ABF6)
Key		From		To		Description		Condition		FTGroup
REGION		89		91		Substrate binding (By similarity)		N-x-E
ACT_SITE		104		104		Proton donor (By similarity)		E
METAL		102		102		Zinc; catalytic (By similarity)		H		1
METAL		129		129		Zinc; catalytic (By similarity)		C		1
METAL		132		132		Zinc; catalytic (By similarity)		C		1

Size range:	292-309 amino acids
Related UniRules:	None
Template:	P0ABF6 (CDD_ECOLI)
Scope:	Bacteria; Gammaproteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None