HAMAP rule MF_01583
General rule information
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| Accession | MF_01583 |
| Dates | 4-OCT-2007 (Created)
1-JUN-2023 (Last updated, Version 19) |
| Name | Thr_Ser_transp_TdcC |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P0AAD8 (TDCC_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01583 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | TDCC |
| Protein name | RecName: Full=Threonine/serine transporter TdcC; AltName: Full=H(+)/threonine-serine symporter; |
| Gene name | Name=tdcC; |
Comments
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| FUNCTION | Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). |
| CATALYTIC ACTIVITY | Reaction=H(+)(in) + L-threonine(in) = H(+)(out) + L-threonine(out); Xref=Rhea:RHEA:28883, ChEBI:CHEBI:15378, ChEBI:CHEBI:57926; PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:28885; |
| CATALYTIC ACTIVITY | Reaction=H(+)(in) + L-serine(in) = H(+)(out) + L-serine(out); Xref=Rhea:RHEA:28887, ChEBI:CHEBI:15378, ChEBI:CHEBI:33384; PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:28889; |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| SIMILARITY | Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. |
Keywords
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| Amino-acid transport |
| Cell membrane |
| Cell inner membrane |
| Membrane |
| Symport |
| Transmembrane |
| Transport |
| Transmembrane helix |
Gene Ontology
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| GO:0015171; Molecular function:amino acid transmembrane transporter activity |
| GO:0015293; Molecular function:symporter activity |
| GO:0006865; Biological process:amino acid transport |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| NCBIfam | TIGR00814; Stp; 1; |
| General | Transmembrane; -; 11; |
Features
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Additional information
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| Size range | 442-443 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |