HAMAP rule MF_01587

General rule information [?]

Accession	MF_01587
Dates	15-NOV-2007 (Created) 28-APR-2022 (Last updated, Version 14)
Name	DNA_ligase_B
Scope(s)	Bacteria Gammaproteobacteria
Template(s)	P25772 (LIGB_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_01587 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	LIGB
Protein name	RecName: Full=DNA ligase B; EC=6.5.1.2; AltName: Full=Polydeoxyribonucleotide synthase [NAD(+)] B;
Gene name	Name=ligB;

Comments [?]

FUNCTION	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
CATALYTIC ACTIVITY	Reaction=NAD(+) + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho- (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + beta- nicotinamide D-nucleotide.; EC=6.5.1.2;
SIMILARITY	Belongs to the NAD-dependent DNA ligase family. LigB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0003911; Molecular function:DNA ligase (NAD+) activity

GO:0006259; Biological process:DNA metabolic process

Cross-references [?]