HAMAP

Accession	MF_01589
Dates	29-NOV-2007 (Created) 2-DEC-2011 (Last updated, Version 10)

Data class

Protein

Predictors

HAMAP; MF_01589; [distribution of match scores in UniProtKB];[seed alignment for MF_01589]

Names

tRNA_methyltr_CmoA

Identifier

CMOA

Protein name

RecName: Full=tRNA (cmo5U34)-methyltransferase; EC=2.1.1.-;

Gene name

cmoA

FUNCTION: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity).

SUBUNIT: Monomer (By similarity).

SIMILARITY: Belongs to the methyltransferase superfamily. CmoA family.

Pfam	PF08241; Methyltransf_11; 1; PF08242; Methyltransf_12; 1;
PIRSF	PIRSF006325; MeTrfase_bac; 1;
TIGRFAMs	TIGR00740; Methyltrans_bac; 1;

Methyltransferase, S-adenosyl-L-methionine, Transferase, tRNA processing.

GO:0008757; Molecular function: S-adenosylmethionine-dependent methyltransferase activity.
GO:0006400; Biological process: tRNA modification.

From: CMOA_HAEIN (P43985)
Key		From		To		Description		Condition		FTGroup
REGION (Optional)		63		65		S-adenosyl-L-methionine binding (By similarity)		G-x-S
REGION (Optional)		116		117		S-adenosyl-L-methionine binding (By similarity)		D-[ILV]
BINDING (Optional)		38		38		S-adenosyl-L-methionine (By similarity)		Y
BINDING (Optional)		88		88		S-adenosyl-L-methionine (By similarity)		D
BINDING (Optional)		131		131		S-adenosyl-L-methionine (By similarity)		N
BINDING (Optional)		198		198		Substrate (Potential)		R

Size range:	228-274 amino acids
Related UniRules:	None
Template:	Q7CQC4 (CMOA_SALTY); P43985 (CMOA_HAEIN): [Recover all]
Scope:	Bacteria; Oscillatoriales Bacteria; Staphylococcus Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in YERPB, YERPS
Plasmid encoded:	None