HAMAP rule MF_01592
General rule information
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| Accession | MF_01592 |
| Dates | 14-DEC-2007 (Created)
19-NOV-2022 (Last updated, Version 14) |
| Name | Nudix_NudL |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | None (); [ Recover all ] |
| Triggered by |
HAMAP; MF_01592 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | NUDL |
| Protein name | RecName: Full=Uncharacterized Nudix hydrolase NudL; EC=3.6.1.-; |
| Gene name | Name=nudL; |
Comments
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| FUNCTION | Probably mediates the hydrolysis of some nucleoside diphosphate derivatives. |
| case <FTGroup:1> | |
| COFACTOR | Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Name=Mg(2+); Xref=ChEBI:CHEBI:18420; |
| end case | |
| SIMILARITY | Belongs to the Nudix hydrolase family. PCD1 subfamily. |
Keywords
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| Hydrolase | |
| case <FTGroup:1> | |
| Magnesium | |
| Manganese | |
| Metal-binding | |
| end case | |
Gene Ontology
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| GO:0016818; Molecular function:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | |
| case <FTGroup:1> | |
| GO:0000287; Molecular function:magnesium ion binding | |
| GO:0030145; Molecular function:manganese ion binding | |
| end case | |
Cross-references
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| Pfam | PF00293; NUDIX; 1; |
| PROSITE | PS51462; NUDIX; 1; |
| PROSITE | PS00893; NUDIX_BOX; 1; |
| PROSITE | PS01293; NUDIX_COA; 1; |
Features
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| From: NUDL_ECOLI (P43337) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOTIF | 67 | 89 | /note="Nudix box" | |||||||||
| BINDING | 83 | 83 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
E | 1 | |||||||
| BINDING | 87 | 87 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
E | 1 | |||||||
Additional information
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| Size range | 187-199 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | The function of this protein is currently unknown, we have therefore restricted this family to the Enterobacterales. |