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HAMAP annotation rule: MF_01599
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General rule information

Accession MF_01599
Dates 10-APR-2008 (Created)
16-JUL-2010 (Last updated, Version 10)
Data class Protein
Predictors HAMAP; MF_01599; [distribution of match scores in UniProtKB];[seed alignment for MF_01599]
Names NhaB


Propagated annotation

Identifier, protein and gene names
Identifier NHAB
Protein name
RecName: Full=Na(+)/H(+) antiporter nhaB;
AltName: Full=Sodium/proton antiporter nhaB;
Gene name nhaB
Comments
FUNCTION: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons (By similarity).

case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).
end case

SIMILARITY: Belongs to the nhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
Cross-references
Pfam PF06450; NhaB; 1;
PRINTS PR00173; EDTRNSPORT; 1;
TIGRFAMs TIGR00774; NhaB; 1;
General Transmembrane; -; 10-13; trigger=Yes;
Keywords
Antiport, Cell membrane.

case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane.
end case

Ion transport, Membrane, Sodium, Sodium transport, Transmembrane, Transport, Transmembrane helix.
Gene Ontology
GO:0015297; Molecular function: antiporter activity.
GO:0015081; Molecular function: sodium ion transmembrane transporter activity.
GO:0006814; Biological process: sodium ion transport.
GO:0005886; Cellular component: plasma membrane.


Additional information

Size range: 499-533 amino acids
Related UniRules: None
Template: P0AFA7 (NHAB_ECOLI); Q9I2S5 (NHAB_PSEAE); Q56577 (NHAB_VIBAL); Q87N04 (NHAB_VIBPA): [Recover all]
Scope: Bacteria; Gammaproteobacteria
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences