HAMAP

Accession	MF_01614
Dates	1-JUN-2005 (Created) 25-NOV-2009 (Last updated, Version 8)

Data class

Protein

Predictors

HAMAP; MF_01614; [distribution of match scores in UniProtKB];[seed alignment for MF_01614]

Names

NamA

Identifier

NAMA

Protein name

RecName: Full=NADPH dehydrogenase; EC=1.6.99.1; AltName: Full=Xenobiotic reductase;

Gene name

namA

FUNCTION: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes (By similarity).

CATALYTIC ACTIVITY: NADPH + acceptor = NADP(+) + reduced acceptor.

COFACTOR: FMN (By similarity).

SUBUNIT: Homotetramer (By similarity).

SIMILARITY: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.

Pfam	PF00724; Oxidored_FMN; 1;

Flavoprotein, FMN, NADP, Oxidoreductase.

GO:0003959; Molecular function: NADPH dehydrogenase activity.

From: NAMA_BACSU (P54550)
Key		From		To		Description		Condition		FTGroup
NP_BIND		23		27		FMN (By similarity)		[SP]-P-M-C-M
BINDING		28		28		Substrate (By similarity)		Y
BINDING		164		164		Substrate (By similarity)		H
BINDING		167		167		Substrate (By similarity)		H
BINDING		215		215		FMN (By similarity)		R
BINDING		308		308		FMN (By similarity)		R

Size range:	337-346 amino acids
Related UniRules:	None
Template:	P54550 (NAMA_BACSU)
Scope:	Bacteria; Bacillales Bacteria; Clostridiales
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None