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| HAMAP annotation rule MF_01629 |
| Accession | MF_01629 |
| Dates | 14-DEC-2005 (Created) 7-OCT-2011 (Last updated, Version 16) |
| Name | PdxH |
| Scope | Bacteria; Actinobacteria Bacteria; Bacteroidetes Bacteria; Cyanobacteria Bacteria; Deinococcus-Thermus Bacteria; Planctomycetes Bacteria; Proteobacteria Bacteria; Spirochaetes |
| Triggered by |
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| FUNCTION | Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity). |
| CATALYTIC ACTIVITY | Pyridoxamine 5'-phosphate + H(2)O + O(2) = pyridoxal 5'-phosphate + NH(3) + H(2)O(2). |
| Pyridoxine 5'-phosphate + O(2) = pyridoxal 5'-phosphate + H(2)O(2). | |
| COFACTOR | Binds 1 FMN per subunit (By similarity). |
| PATHWAY | Cofactor biosynthesis; B6 vitamer interconversion; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; step 1/1. |
| Cofactor biosynthesis; B6 vitamer interconversion; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate; step 1/1. | |
| SUBUNIT | Homodimer (By similarity). |
| SIMILARITY | Belongs to the pyridoxamine 5'-phosphate oxidase family. |
GO:0004733; Molecular function: pyridoxamine-phosphate oxidase activity.
GO:0010181; Molecular function: FMN binding.
GO:0042816; Biological process: vitamin B6 metabolic process.
GO:0010181; Molecular function: FMN binding.
GO:0042816; Biological process: vitamin B6 metabolic process.
| From: PDXH_ECOLI (P0AFI7) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| NP_BIND | 82 | 83 | FMN (By similarity) | [YF]-[TS] | ||||||||
| NP_BIND | 146 | 147 | FMN (By similarity) | Q-S | ||||||||
| REGION (Optional) | 14 | 17 | Substrate binding (By similarity) | R-x-x-Y | ||||||||
| REGION | 197 | 199 | Substrate binding (By similarity) | R-x-[HN] | ||||||||
| BINDING | 67 | 67 | FMN (By similarity) | R | ||||||||
| BINDING | 70 | 70 | FMN; via amide nitrogen (By similarity) | L | ||||||||
| BINDING | 72 | 72 | Substrate (By similarity) | [KR] | ||||||||
| BINDING | 89 | 89 | FMN (By similarity) | K | ||||||||
| BINDING | 129 | 129 | Substrate (By similarity) | Y | ||||||||
| BINDING | 133 | 133 | Substrate (By similarity) | R | ||||||||
| BINDING (Optional) | 137 | 137 | Substrate (By similarity) | S | ||||||||
| Size range: | 192-267 amino acids |
| Related Rules: | None |
| Templates: | P0AFI7 (PDXH_ECOLI); P65682 (PDXH_MYCTU): [Recover all] |
| Fusion: | None |