HAMAP

Accession	MF_01639
Dates	29-NOV-2006 (Created) 7-OCT-2011 (Last updated, Version 12)

Data class

Protein

Predictors

HAMAP; MF_01639; [distribution of match scores in UniProtKB];[seed alignment for MF_01639]

Names

PdxY

Identifier

PDXY

Protein name

RecName: Full=Pyridoxamine kinase; Short=PM kinase; EC=2.7.1.35;

Gene name

pdxY

FUNCTION: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine (By similarity).

CATALYTIC ACTIVITY: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.

SIMILARITY: Belongs to the pyridoxine kinase family.

Pfam	PF00294; PfkB; 1; PF08543; Phos_pyr_kin; 1;
TIGRFAMs	TIGR00687; Pyridox_kin; 1;

ATP-binding, Kinase, Metal-binding, Nucleotide-binding, Transferase, Zinc.

GO:0008270; Molecular function: zinc ion binding.
GO:0005524; Molecular function: ATP binding.
GO:0004340; Molecular function: glucokinase activity.
GO:0006096; Biological process: glycolysis.

From: PDXY_ECOLI (P77150)
Key		From		To		Description		Condition		FTGroup
NP_BIND		182		183		ATP (By similarity)		K-H

Key		From		To		Description		Condition		FTGroup
NP_BIND		208		223		ATP (By similarity)		[CS]-R-P-L-V-[DE]-F-[EG]-x-R-Q-P-V-G-V-G

Key		From		To		Description		Condition		FTGroup
BINDING		10		10		Substrate (By similarity)		S
BINDING		45		45		Substrate (By similarity)		T
BINDING		224		224		Substrate (By similarity)		D

Size range:	283-299 amino acids
Related UniRules:	None
Template:	P77150 (PDXY_ECOLI)
Scope:	Bacteria; Actinobacteria Bacteria; Deinococci Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	SALTI contains a C-terminal deletion removing the last 68 aa, and may therefore be non-functional. This sequence is not shown in alignment and was not taken into account for the size range field.