HAMAP

Accession	MF_01650
Dates	17-APR-2008 (Created) 2-DEC-2011 (Last updated, Version 8)

Data class

Protein

Predictors

HAMAP; MF_01650; [distribution of match scores in UniProtKB];[seed alignment for MF_01650]

Names

HcaC

Identifier

HCAC

Protein name

RecName: Full=3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit; AltName: Full=Digoxigenin ferredoxin subunit;

Gene name

hcaC

FUNCTION: Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively. This protein seems to be a 2Fe-2S ferredoxin (By similarity).

PATHWAY: Aromatic compound metabolism; 3-phenylpropanoate degradation.

SUBUNIT: This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD) (By similarity).

SIMILARITY: Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin component family.

SIMILARITY: Contains 1 Rieske domain.

PROSITE	PS51296; RIESKE; 1; trigger=PRU00628;
Pfam	PF00355; Rieske; 1;

2Fe-2S, Aromatic hydrocarbons catabolism, Electron transport, Iron, Iron-sulfur, Metal-binding, Transport.

GO:0008695; Molecular function: 3-phenylpropionate dioxygenase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

From: HCAC_ECOLI (P0ABW0)
Key		From		To		Description		Condition		FTGroup
METAL		42		42		Iron-sulfur (2Fe-2S) (By similarity)		C
METAL		44		44		Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity)		H
METAL		62		62		Iron-sulfur (2Fe-2S) (By similarity)		C
METAL		65		65		Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity)		H

Size range:	105-106 amino acids
Related UniRules:	None
Template:	P0ABW0 (HCAC_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None