HAMAP

Accession	MF_01651
Dates	17-APR-2008 (Created) 6-JUL-2012 (Last updated, Version 9)

Name

HcaD

Scope

Bacteria; Enterobacteriaceae

Triggered by

HAMAP; MF_01651 (Get profile general information and statistics)

Identifier

HCAD

Protein name

RecName: Full=3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component; EC=1.18.1.3; AltName: Full=Digoxigenin system ferredoxin--NAD(+) reductase component;

Gene name

hcaD

FUNCTION	Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively (By similarity).
CATALYTIC ACTIVITY	Reduced ferredoxin + NAD(+) = oxidized ferredoxin + NADH.
COFACTOR	FAD (By similarity).
PATHWAY	Aromatic compound metabolism; 3-phenylpropanoate degradation.
SUBUNIT	This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD) (By similarity).
SIMILARITY	Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.

Aromatic hydrocarbons catabolism
FAD
Flavoprotein
NAD
Oxidoreductase

GO:0008695; Molecular function: 3-phenylpropionate dioxygenase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

Pfam	PF00070; Pyr_redox; 1;
	PF07992; Pyr_redox_2; 1;
PRINTS	PR00368; FADPNR; 1;

From: HCAD_ECOLI (P77650)

Key

From

To

Description

Tag

Condition

FTGroup

NP_BIND

5

36

FAD (Potential)

NP_BIND

146

174

NAD (Potential)

Size range:	394-410 amino acids
Related Rules:	None
Template:	P77650 (HCAD_ECOLI)
Fusion:	None

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