HAMAP

Accession	MF_01651
Dates	17-APR-2008 (Created) 2-DEC-2011 (Last updated, Version 7)

Data class

Protein

Predictors

HAMAP; MF_01651; [distribution of match scores in UniProtKB];[seed alignment for MF_01651]

Names

HcaD

Identifier

HCAD

Protein name

RecName: Full=3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component; EC=1.18.1.3; AltName: Full=Digoxigenin system ferredoxin--NAD(+) reductase component;

Gene name

hcaD

FUNCTION: Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively (By similarity).

CATALYTIC ACTIVITY: Reduced ferredoxin + NAD(+) = oxidized ferredoxin + NADH.

COFACTOR: FAD (By similarity).

PATHWAY: Aromatic compound metabolism; 3-phenylpropanoate degradation.

SUBUNIT: This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD) (By similarity).

SIMILARITY: Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.

Pfam	PF00070; Pyr_redox; 1; PF07992; Pyr_redox_2; 1;
PRINTS	PR00368; FADPNR; 1;

Aromatic hydrocarbons catabolism, FAD, Flavoprotein, NAD, Oxidoreductase.

GO:0008695; Molecular function: 3-phenylpropionate dioxygenase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

From: HCAD_ECOLI (P77650)
Key		From		To		Description		Condition		FTGroup
NP_BIND		5		36		FAD (Potential)
NP_BIND		146		174		NAD (Potential)

Size range:	394-410 amino acids
Related UniRules:	None
Template:	P77650 (HCAD_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	in ECO24
Plasmid encoded:	None