Annotation rule MF_01651
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General rule information [?]

Accession MF_01651
Dates 17-APR-2008 (Created)
6-JUL-2012 (Last updated, Version 9)
Name HcaD
Scope Bacteria; Enterobacteriaceae
Template P77650 (HCAD_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
HCAD
Protein name
RecName: Full=3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component;
EC=1.18.1.3;
AltName: Full=Digoxigenin system ferredoxin--NAD(+) reductase component;
Gene name
hcaD

Comments [?]

Function Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively (By similarity).
Catalytic activity Reduced ferredoxin + NAD(+) = oxidized ferredoxin + NADH.
Cofactor FAD (By similarity).
Pathway Aromatic compound metabolism; 3-phenylpropanoate degradation.
Subunit This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD) (By similarity).
Similarity Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.

Keywords [?]


Gene Ontology [?]

GO:0008695; Molecular function: 3-phenylpropionate dioxygenase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

Cross-references [?]

Pfam PF00070; Pyr_redox; 1;
PF07992; Pyr_redox_2; 1;
PRINTS PR00368; FADPNR; 1;

Features [?]

From: HCAD_ECOLI (P77650)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     5     36       FAD (Potential)        
NP_BIND     146     174       NAD (Potential)        

Additional information [?]

Size range 394-410 amino acids
Related rules None
Fusion None