Annotation rule MF_01653
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General rule information [?]

Accession MF_01653
Dates 29-APR-2008 (Created)
2-OCT-2012 (Last updated, Version 13)
Name MhpB
Scope Bacteria; Actinobacteria
Bacteria; Proteobacteria
Template P0ABR9 (MHPB_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MHPB
Protein name
RecName: Full=2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase;
EC=1.13.11.16;
AltName: Full=3-carboxyethylcatechol 2,3-dioxygenase;
Gene name
mhpB

Comments [?]

Function Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively (By similarity).
Catalytic activity 3-(2,3-dihydroxyphenyl)propanoate + O(2) = (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate.
(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + O(2) = (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate.
Cofactor Fe(2+) ion (By similarity).
Pathway Aromatic compound metabolism; 3-phenylpropanoate degradation.
Subunit Homotetramer (By similarity).
Similarity Belongs to the LigB/MhpB extradiol dioxygenase family.

Keywords [?]


Gene Ontology [?]

GO:0005506; Molecular function: iron ion binding.
GO:0047070; Molecular function: 3-carboxyethylcatechol 2,3-dioxygenase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

Cross-references [?]

Pfam PF02900; LigB; 1;

Features [?]

From: MHPB_ECOLI (P0ABR9)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     115     115       Proton donor (By similarity)     H  
ACT_SITE     179     179       Proton acceptor (By similarity)     H  

Additional information [?]

Size range 311-331 amino acids
Related rules None
Fusion None