HAMAP

Accession	MF_01655
Dates	30-APR-2008 (Created) 17-FEB-2010 (Last updated, Version 10)

Data class

Protein

Predictors

HAMAP; MF_01655; [distribution of match scores in UniProtKB];[seed alignment for MF_01655]

Names

MhpD

Identifier

MHPD

Protein name

RecName: Full=2-keto-4-pentenoate hydratase; EC=4.2.1.80; AltName: Full=2-hydroxypentadienoic acid hydratase;

Gene name

mhpD

FUNCTION: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid (By similarity).

CATALYTIC ACTIVITY: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H(2)O.

COFACTOR: Divalent metal ions (By similarity).

PATHWAY: Aromatic compound metabolism; 3-phenylpropanoate degradation.

SIMILARITY: Belongs to the hydratase/decarboxylase family. MhpD subfamily.

Pfam	PF01557; FAA_hydrolase; 1;

Aromatic hydrocarbons catabolism, Lyase.

GO:0008684; Molecular function: 2-oxopent-4-enoate hydratase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

Size range:	260-271 amino acids
Related UniRules:	None
Template:	P77608 (MHPD_ECOLI)
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in DECAR, PSEPU
Plasmid encoded:	in PSEPU