HAMAP

Accession	MF_01665
Dates	8-JUL-2008 (Created) 24-SEP-2010 (Last updated, Version 7)

Data class

Protein

Predictors

HAMAP; MF_01665; [distribution of match scores in UniProtKB];[seed alignment for MF_01665]

Names

HemeA_synth_type2

Identifier

CTAA

Protein name

RecName: Full=Heme A synthase; Short=HAS; EC=1.3.-.-; AltName: Full=Cytochrome aa3-controlling protein;

Gene name

ctaA

FUNCTION: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity).

PATHWAY: Porphyrin metabolism; heme A biosynthesis; heme A from heme O: step 1/1.

SUBUNIT: Interacts with CtaB (By similarity).

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

SIMILARITY: Belongs to the COX15/CtaA family. Type 2 subfamily.

Pfam	PF02628; COX15-CtaA; 1;
General	Transmembrane; -; 8; trigger=Yes;

Cell membrane, Heme biosynthesis, Membrane, Oxidoreductase, Transmembrane, Transmembrane helix.

GO:0006784; Biological process: heme a biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

From: CTAA_RHOS4 (Q3IXW9)
Key		From		To		Description		Condition		FTGroup
BINDING		360		360		Substrate (By similarity)		H

Size range:	325-391 amino acids
Related UniRules:	MF_01664 (CTAA)
Template:	Q3IXW9 (CTAA_RHOS4)
Scope:	Bacteria; Flavobacteria Bacteria; Alphaproteobacteria Bacteria; Betaproteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in ACICJ
Plasmid encoded:	in RHOS5
Comments:	COX15/ctaA type 1 subfamily in MF_01664.