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Annotation rule MF_01672
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General rule information [?]

Accession MF_01672
Dates 29-SEP-2008 (Created)
13-OCT-2014 (Last updated, Version 9)
Name IolE
Scope Bacteria; Firmicutes
Bacteria; Gammaproteobacteria
Bacteria; Tenericutes
Template P42416 (IOLE_BACSU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
IOLE
Protein name
RecName: Full=Inosose dehydratase;
EC=4.2.1.44;
AltName: Full=2-keto-myo-inositol dehydratase;
Short=2KMI dehydratase;
Gene name
iolE

Comments [?]

Function Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
Catalytic activity 2,4,6/3,5-pentahydroxycyclohexanone = 3,5/4-trihydroxycyclohexa-1,2-dione + H(2)O.
Cofactor glutathione
Co(2+)
Mn(2+)
case <OC:Firmicutes>
Pathway Polyol metabolism; myo-inositol degradation into acetyl-CoA; acetyl-CoA from myo-inositol: step 2/7.
end case
Similarity Belongs to the IolE/MocC family.

Keywords [?]


Gene Ontology [?]

GO:0030145; Molecular function: manganese ion binding.
GO:0050114; Molecular function: myo-inosose-2 dehydratase activity.
GO:0019310; Biological process: inositol catabolic process.

Cross-references [?]

Pfam PF01261; AP_endonuc_2; 1;

Additional information [?]

Size range 297-308 amino acids
Related rules None
Fusion None